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| 1 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 4 |
| 2 | Distribution of tobacco constituents in tobacco leaf tissue tobacco-special nitrosamines,nitrate,nitrite,and alkaloids显示文摘 | Burton H R Dye N K Bush L E | 1992 | Journal of Agricultural and Food Chemistry1992，40，6： | 1 |
| 3 | Relationship between tobacco-specific nitrosamines and nitrate from different air-cured tobacco varieties显示文摘 | BURTON H R DYE N K BUSH L P | 1994 | Agric food Chem1994，42，： | 1 |
| 4 | Deterministic inventory model for deteriorating items with capacity constraint and time-proportional backlogging rate显示文摘 | Dye C Y Ouyang L Y Hsieh T P | 2007 | European Journal of Operational Research2007，178，3： | 1 |
| 5 | An EOQ model for perishable items under stock-dependent selling rate and time-dependent partial backlogging显示文摘 | DYE C Y OUYANG L Y | 2005 | European Journal of Operational Research2005，163，3： | 1 |
| 6 | Distribution of tobacco-specific nitr osamines in tobacco leaf tissue (1)tobacco-specific, nitrate and alkaloids显示文摘 | Burton H R Dye N K Bush L P | 1989 | J Agric Food Chem1989，40，： | 1 |
| 7 | The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates显示文摘 | MARTIN L D KRUNKOSKY T M DYE J A | 1997 | Environ Health Persp1997，105，5： | 1 |
| 8 | In situ syn- chrotron diffraction of the electrochemical reduction path- way ofTiO2显示文摘 | Bhagat R Dye D Raghunathan S L | 2010 | Acta Materialia2010，58，15： | 1 |
| 9 | An EOQ model for perishable items under stock-dependent selling rate and time-dependent partial backlogging 显示文摘 | Dye C Y Ouyang L Y | 2005 | European Journal of Operational Research2005，163，4： | 1 |
| 10 | Relationship between tobacco-specific nitrosa mines and nitrate from different air-cured tobacco varieties显示文摘 | Burton H R Dye N K Bush L P | 1994 | Agric food Chem1994，42，： | 1 |
| 11 | Phenotype of the endothelium in the human term placenta 显示文摘 | Dye J F Jablenska R Donnelly J L | 2001 | Placenta2001，22，1： | 1 |
| 12 | Distribution of tobacco constituents in tobacco leaf tissue I tobacco-special nitrosamines,nitrate,nitrite and alkaloids显示文摘 | Burton H R Dye N K Bush L P | 1992 | Journal of Agricultural and Food Chemistry1992，40，6： | 1 |
| 13 | Relationship between tobacco-specifie nitrosarnines and nitrate from different air-cured tobacco varieties显示文摘 | Burton H R Dye N K Bush L P | 1994 | Agric food Chem1994，42，： | 1 |
| 14 | Cyclic AMP and acidic fibroblast growth factor have opposing effects on tight and adherens junctions in microvascular endothelial cells in vitro显示文摘 | Dye J F Leach L Clark P | 2001 | Microvasc Res2001，62，2： | 1 |
| 15 | A model evalu- ation of non-inductive graupel-ice charging in the early electrifi- cation of a mountain thunderstorm显示文摘 | Ziegler C L MacGorman D R Dye J E | 1991 | J Geophys Res1991，96，7： | 1 |
| 16 | Relation between tobacco varieties 显示文摘 | Burton H R Naewanne K Dye Bush L P | 1992 | JAgric Food Chem1992，42，： | 1 |
| 17 | A model evaluation of noninductive graupel-ice charging in the early electrification of a mountain thunderstorm显示文摘 | Ziegler C L MacC-orman D R Dye J E | 1991 | J Geophys Res1991，96，12： | 1 |
| 18 | The effects of flavonoid and other polyphenol consumption on cognitive performance: a systematic research review of human experimental and epidemiological studies显示文摘 | LAMPORT D J DYE L WIGHTMAN J D | 2012 | Nutrition and Aging2012，1，1： | 1 |
| 19 | Ultralong single-wall carbon nanotubes显示文摘 | ZHENG L X O'CONNELL M J DOORN S K LIAO X Z ZHAO Y H AKHADOV E A HOFFBAUER M A ROOP B J JIA Q X DYE R C PETERSON D E HUANG S M LIU J ZHU Y T | 2004 | Naturematerials2004，3，： | 1 |
| 20 | Isolation and Antimicrobial Susceptibilities of Bacterial Pathogens from Bovine Pneumonia: 1994-2002 显示文摘 | Welsh R D Dye L B Payton M E | 2004 | J Vet Diagn Invest2004，16，： | 1 |
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