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	题名	作者	年代	出处	被引量
1	Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells 显示文摘	van Baren N Bonnet MC Dreno B	2005	J Clin Oncol2005，23，35：	1
2	ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology显示文摘	Dreno B Khammari A Orain N	2007	Dermatology2007，214，1：	1
3	Prognostic factors in Sezary syndrome:a study of 28 patients显示文摘	Foulc P N' Guyen JM Dreno B	2003	Br J Dermatol2003，149，6：	1
4	显示文摘	Bernier C Dreno B	2001	Ann Dermatol Venereol2001，128，5：	1
5	Acne:physical treatment显示文摘	Dreno B	2004	Clin Dermato12004，22，5：	1
6	Descriptive epidemiological study of acne on scholar pupils in France during autumn 1996 显示文摘	Daniel F Dreno B Poli F	2000	Ann Dermatol Venereol2000，127，3：	1
7	Multicenter randomized comparative double-blind controlled clinical trial of the safety and efficacy of zinc gluconate versus minocycline hydrochloride in the treatment of inflammatory acne vulgaris显示文摘	Dreno B Moyse D Alirezai M	2001	Dermatol2001，203，2：	1
8	痤疮丙酸杆菌激活的toll样受体显示文摘Background: The bacterium Propionibacterium acnes is involved in the induction and maintenance of the inflammatory phase of acne. Recent studies have found that keratinocytes express toll-like receptors (TLRs) implicated in immediate immunity. No studies have, to date, been carried out on the action of P. acnes upon TLR activation in keratinocytes. Objectives: Focusing on the inflammatory phase of acne, to clarify the role of P. acnes in immediate immunity by inducing expression of TLR- 2 and TLR- 4 by keratinocytes. We also studied how the secretion and expression of matrix metalloproteinase (MMP)- 9 is induced by P. acnes. Methods: The work was carried out on two levels: in vivo with the study of the expression of TLR- 2 and TLR- 4 proteins in biopsies of acne lesions and in vitro on cultured keratinocyte monolayers to study the modulating effects of P. acnes on the expression of TLR- 2 and TLR- 4 and also on the expression and secretion of MMP- 9. Results: Our findings reveal that in vivo TLR- 2 and TLR- 4 expression is increased in the epidermis of acne lesions. In vitro, an increase in TLR- 2 and TLR- 4 expression by human keratinocytes occurred in the first hours of incubatio with bacterial fractions as well as an increase of the expression and secretion by the keratinocytes of MMP- 9, which plays a role in inflammation. Conclusions: This work demonstrates that P. acnes induces TLR expression and that this mechanism could play an essential role in acnelinked inflammation. These receptors could be involved notably in acute acne.	Jugeau S. Tenaud I. Knol A.C. B. Dreno 刘艳	2006	世界核心医学期刊文摘(皮肤病学分册)2006，2，3：	1
9	Expert Opinion : Efficacy of superficial chemical peels in active acne management-what can we learn from the literature today? Evidence-based recommendations 显示文摘	Dreno B Fischer T Perosino E	2011	J Eur Acad Dermatol Venereol2011，25，6：	1
10	ECCA grading scale:an original validated acne scar grading scale for clinical practice in dermatology 显示文摘	Dreno B Khammari A Orain N	2007	Dermatology2007，214，：	1
11	Minocycline显示文摘	Bernier C Dreno B	2001	Ann Dermatol Venereol2001，128，：	1
12	Rosacea - global diversity and optimized outcome : proposed international consensus from the Rosacea Inter- national Export Group 显示文摘	Elewski BE Draelos Z Dreno B	2011	J Eur Aead Dermatol Venereol2011，25，2：	1
13	In vitro modulation of TLR-2, CDld and IL-10 by adapalene on normal human skin and acne inflammatory lesions 显示文摘	Tenaud I Khammari A Dreno B	2007	Exp Dermatol2007，16，6：	1
14	Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells显示文摘	van Baren N Bonnet MC Dreno B	2005	J Clin Oncol2005，23，35：	1
15	Prognostic factors in Sezary syndrome: A study of 28 patients显示文摘	Foulc P N'Guyen JM Dreno B	2003	Br J Dermatol2003，149，6：	1
16	Primary cutaneous CD30^+ anaplastic large cell lymphoma responds to imiquimod cream显示文摘	Ehst BD Dreno B Vonderheid EC	2008	Eur J Dermatol2008，18，4：	1
17	Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells显示文摘	Van Baren N Bonnet MC Dreno B	2005	J Clin Oncol2005，23，35：	1
18	Epidemiology of acne显示文摘	Dreno B Poli F	2003	Dermatology2003，206，1：	1
19	Epidemiology of acne显示文摘	Dreno B Poli F	2003	Dermatology2003，206，：	1
20	Randomized tri- al of adoptive transfer of melanoma tumor-infiltrating lym- phocytes as adjuvant therapy for stage III melanoma 显示文摘	Dreno B Nguyen JM Khammari A	2002	Cancer Immunol Immunother2002，51，：	1

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