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| 1 | Peritoneal carcinomatosis of colorectal origin:Incidence,prognosis and treatment options显示文摘Peritoneal carcinomatosis (PC) is one manifestation of metastatic colorectal cancer (CRC). Tumor growth on intestinal surfaces and associated fluid accumulation eventually result in bowel obstruction and incapacitating levels of ascites, which profoundly affect the quality of life for affected patients. PC appears resistant to traditional 5-fluorouracil-based chemotherapy, and surgery was formerly reserved for palliative purposes only. In the absence of effective treatment, the histori-cal prognosis for these patients was extremely poor, with an invariably fatal outcome. These poor outcomes likely explain why PC secondary to CRC has received little attention from oncologic researchers. Thus, data are lacking regarding incidence, clinical disease course, and accurate treatment evaluation for patients with PC. Recently, population-based studies have revealed that PC occurs relatively frequently among patients withCRC. Risk factors for developing PC have been identi-fied:right-sided tumor, advanced T-stage, advanced N-stage, poor differentiation grade, and younger age at diagnosis. During the past decade, both chemother-apeutical and surgical treatments have achieved prom-ising results in these patients. A chance for long-term survival or even cure may now be offered to selected patients by combining radical surgical resection with intraperitoneal instillation of heated chemotherapy. This combined procedure has become known as hy-perthermic intraperitoneal chemotherapy. This edito-rial outlines recent advancements in the medical and surgical treatment of PC and reviews the most recent information on incidence and prognosis of this disease. Given recent progress, treatment should now be considered in every patient presenting with PC. | Yvonne LB Klaver Valery EPP Lemmens Simon W Nienhuijs Misha DP Luyer Ignace HJT de Hingh | 2012 | World Journal of Gastroenterology2012，18，39： | 9 |
| 2 | CDX2 is a useful marker of intestinal-type differentiation : a tissue microarray-based study of 629 tumors from various sites 显示文摘 | De Lott LB Morrison C Suster S | 2005 | Arch Pathol Lab MED2005，129，9： | 1 |
| 3 | Clinical and immunologic evaluation of 31 patients with acute schistosomiasis mansoni 显示文摘 | De Jesus AR Silva A Santana LB | 2002 | J Infect Dis2002，185，1： | 1 |
| 4 | Simultaneous laparoscopic resection of primary colorectal cancer and associated liver metastases: a systematic review 显示文摘 | Lupinacci RM Andraus W De Paiva Haddad LB | 2014 | Tech Coloproctol2014，18，2： | 1 |
| 5 | Low-dose prednisone induces rapid reversible axial bone loss in patients with rheumatoid arthritis : a randomized, controlled study 显示文摘 | Laan RF van Riel PL van de Putte LB | 1993 | Ann Intern Med1993，119，10： | 1 |
| 6 | Age related changes of the collagen network of the human heart 显示文摘 | Gazoti Debessa CR Mesiano Maifrino LB Rodfigues de Souza R | 2001 | Mech Ageing Dev2001，122，： | 1 |
| 7 | Association of Randall plaque with collagen fibers and membrane vesicles 显示文摘 | Khan SR Rodriguez DE Gower LB | 2012 | J Urol2012，187，： | 1 |
| 8 | Renal involvement in Henoch- Schonlein purpura: a multivariate analysis of initial prognostic factors 显示文摘 | de Almeida JL Campos LM Paim LB | 2007 | J Pediatr2007，83，3： | 1 |
| 9 | Echocardiography in pulmonary vascular disease显示文摘 | Daniels LB Krummen DE Blanchard DG | 2004 | Cardiol Clin2004，22，： | 1 |
| 10 | Simultaneous laparoscopic resection of primary colorectal cancer and associated liver metastases : a systematic review 显示文摘 | Lupinacci RM Andraus W De Paiva Haddad LB | 2014 | Tech Coloprocto12014，18，2： | 1 |
| 11 | Renal Involvement in He- noch-Sehonlein Purpura: a Multivariate Analysis of Initial Prognostic Factors 显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr ( Rio J)2007，83，3： | 1 |
| 12 | Combined treatment with verapamil,a calcium channel blocker,and B428,a synthetic uPA inhibitor,impairs the metastatic ability of a murine mammary carcinoma显示文摘 | Todaro LB Ladeda V Bal de Kier Joffe E | 2003 | Oncol Rep2003，10，3： | 1 |
| 13 | Cytoplasmic c-Jun N-terminal immunoreactivity: a hallmark of retinal apoptosis显示文摘 | Chiarini LB de Freitas FG Leal-Ferreira ML | 2002 | Cell Mol Neurobiol2002，22，56： | 1 |
| 14 | Reverse hexa-gonal phase nanodispersion of monoolein and oleic acid for topicaldelivery of peptides: in vitro and in vivo skin penetration of cyclos-porin A显示文摘 | LOPES LB FERREIRA DA DE PAULA D | 2006 | Pharm Res2006，23，6： | 1 |
| 15 | Renal involvement inHenoch-Schonlein purpura:a mulitivariate analysis of initial prog-nostic factors显示文摘 | De Almeida JL Campos LM Paim LB | 2007 | J Pediatr(RioJ)2007，83，3： | 1 |
| 16 | The effect of varied stride rate upon shank deceleration in running显示文摘 | Clarke TE Cooper LB Hamill CL Clark DE | | 0，，： | 1 |
| 17 | A tumour necrosis factor alpha polymorphism is not associated with rheumatoid arthritis 显示文摘 | Wilson AG de Vries N van de Putte LB | 1995 | Ann Rheum Dis1995，54，7： | 1 |
| 18 | Childhood T-cell a-cute lymphoblastic leukemia:the Dana-Farber Cancer Institute a-cute lymphoblastic leukemia consortium experience显示文摘 | Goldberg JM Silverman LB Levy DE | 2003 | J Clin Oncol2003，21，19： | 1 |
| 19 | Serrated polyps of the colon: how reproducible is their classification?显示文摘 | Arzu Ensari Banu Bilezik?i Fatima Carneiro Gülen Bülbül Do?usoy Ann Driessen Ay?e Dursun Jean-Fran?ois Flejou Karel Geboes Gert de Hertogh Anne Jouret-Mourin Cord Langner Ir?s D. Nagtegaal Johan Offerhaus Janina Orlowska Ari Ristim?ki Julian Sanz-Ortega B | 2012 | Virchows Archiv2012，，5： | 1 |
| 20 | Dehydration impairsvigilance-related attention in male basketball players显示文摘 | Baker LB Conroy DE Kenney WL | 2007 | Med Sci Sports Exerc、2007，39，： | 1 |
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