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| 1 | Hepatitis B virus genotypes and extrahepatic manifestations显示文摘 | Patrice Cacoub David Saadoun Marc Bourlière Hacene Khiri Agnes Martineau Yves Benhamou Marina Varastet Stanislas Pol Vincent Thibault Michel Rotily Philippe Halfon | 2005 | Journal of Hepatology2005，，5： | 5 |
| 2 | 消融的冰川:加拿大班夫国家公园亚高山带鲍湖中持久性有机氯的主要来源显示文摘有机氯杀虫剂和多氯联苯(PCB)是环境中普遍而稳固的化合物。现已查明,由于它们从温暖的地区逐渐蒸发出来,并在较冷的地区凝聚下来,因而它们富集在寒冷的环境中。在本研究中,我们的结果是,消融的冰川供给阿尔伯达亚高山带湖泊中的有机氯输入量为50%~97%,而提供的水量为73%。对氚的分析结果表明,在夏季的中、晚期,至少10%的冰川消融物是在1950~1970年期间沉积下来的,这期间它受到有机氯更多的污染。这一发现表明,气候变暖可能会使消融的冰川成为日益增多的淡水污染物来源。由于有机物贫乏的冰川粘土对多氯联苯这样的疏水化合物的吸附能力有限,因此冰川水流带来的有机氯大多呈溶解状态。 | Jules M. Blais David W. Schindler Derek C. G. Muir Martin Sharp David Donald MelissaLafrenière Eric Braekevelt William M. J. Strachan 周立志 | 2001 | AMBIO-人类环境杂志2001，30，7： | 4 |
| 3 | 小P值并不能保证可靠结果:以帕金森病的静息态脑功能成像元分析为例显示文摘Thousands of resting state functional magnetic resonance imaging(RS-f MRI)articles have been published on brain disorders.For precise localization of abnormal brain activity,a voxel-level comparison is needed.Because of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1]. | 贾熙泽 赵娜 董昊铭 孙家伟 Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa 陈博宇 陈俊 Stephen Coombes Luc Defebvre Christine Delmaire Kathy Dujardin Fabrizio Esposito 范国光 Federica Di Nardo 冯怡萱 Brett W.Fling Saurabh Garg Moran Gilat Martin Gorges Shu-Leong Ho Fay B.Horak 胡晓 胡晓飞 黄飚 黄沛钰 贾泽娟 Christina Jones Jan Kassubek Lenka Krajcovicova Ajay Kurani 李静 李晴 刘爱萍 刘波 刘虎 刘卫国 Renaud Lopes 娄毓婷 罗巍 Tara Madhyastha 毛妮妮 Grainne McAlonan Martin J.McKeown Shirley Pang Andrea Quattrone Irena Rektorova Alessia Sarica 商慧芳 James M.Shine Priyank Shukla Tomas Slavicek 宋潇鹏 Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt 王健 王珏 Z.Jane Wang 魏鲁庆 邬霞 徐晓俊 闫磊 杨靓 杨万群 姚乃琳 张得龙 张久权 张敏鸣 张艳玲 周彩红 严超赣 左西年 Mark Hallett 吴涛 臧玉峰 | 2021 | Science Bulletin2021，66，21： | 3 |
| 4 | Effects of human immunodeficiency virus on the erythrocyte and megakaryocyte lineages显示文摘Anaemia and thrombocytopenia are haematological disorders that can be detected in many human immunodeficiency virus(HIV)-positive patients during the development of HIV infection. The progressive decline of erythrocytes and platelets plays an important role both in HIV disease progression and in the clinical and therapeutic management of HIV-positive patients. HIV-dependent impairment of the megakaryocyte and erythrocyte lineages is multifactorial and particularly affects survival, proliferation and differentiation of bone marrow(BM) CD34+ haematopoietic progenitor cells, the activity of BM stromal cells and the regulation of cytokine networks. In this review, we analyse the ma-jor HIV-related mechanisms that are involved in the genesis and development of the anaemia and thrombocytopenia observed in HIV positive patients. | Davide Gibellini Alberto Clò Silvia Morini Anna Miserocchi Cristina Ponti Maria Carla Re | 2013 | World Journal of Virology2013，2，2： | 2 |
| 5 | A next-generation marker genotyping platform(AmpSeq)in heterozygous crops:a case study for marker-assisted selection in grapevine显示文摘Marker-assisted selection(MAS)is often employed in crop breeding programs to accelerate and enhance cultivar development,via selection during the juvenile phase and parental selection prior to crossing.Next-generation sequencing and its derivative technologies have been used for genome-wide molecular marker discovery.To bridge the gap between marker development and MAS implementation,this study developed a novel practical strategy with a semi-automated pipeline that incorporates trait-associated single nucleotide polymorphism marker discovery,low-cost genotyping through amplicon sequencing(AmpSeq)and decision making.The results document the development of a MAS package derived from genotyping-by-sequencing using three traits(flower sex,disease resistance and acylated anthocyanins)in grapevine breeding.The vast majority of sequence reads(⩾99%)were from the targeted regions.Across 380 individuals and up to 31 amplicons sequenced in each lane of MiSeq data,most amplicons(83 to 87%)had<10%missing data,and read depth had a median of 220–244×.Several strengths of the AmpSeq platform that make this approach of broad interest in diverse crop species include accuracy,flexibility,speed,high-throughput,low-cost and easily automated analysis. | Shanshan Yang Jonathan Fresnedo-Ramíre Minghui Wang Linda Cote Peter Schweitzer Paola Barba Elizabeth M Takacs Matthew Clark James Luby David C Manns Gavin Sacks Anna Katharine Mansfield Jason Londo Anne Fennell David Gadoury Bruce Reisch Lance Cadle-Davidson Qi Sun | 2016 | Horticulture Research2016，3，1： | 2 |
| 6 | AtbZIP34 is required for Arabidopsis pollen wall patterning and the control of several metabolic pathways in developing pollen显示文摘 | Antónia Gibalová David Reňák Katarzyna Matczuk Nikoleta Dupl’áková David Cháb David Twell David Honys | 2009 | Plant Molecular Biology2009，，5： | 1 |
| 7 | Degradation of sterols and terrigenous organic matter in waters of the Mackenzie Shelf, Canadian Arctic显示文摘 | Jean-Fran?ois Rontani Bruno Charrière Richard Sempéré David Doxaran Frédéric Vaultier Jorien E. Vonk John K. Volkman | 2014 | Organic Geochemistry2014，，： | 1 |
| 8 | Prospective surveillance of imipenem-cilastatin use and associated seizure using a hospital information system显示文摘 | Stanley LP David CC Scott RE | 1993 | Ann Pharmcother1993，27，： | 1 |
| 9 | Biodiversity gap analysis of the protected area system in poorly-documented Chad显示文摘 | David Brugière Paul Scholte | 2013 | Journal for Nature Conservation2013，，： | 1 |
| 10 | Spontaneous rupture of the liver caused by hepatomas显示文摘 | Hermann RE David TE | 1973 | Surgery1973，74，5： | 1 |
| 11 | 18 F-FDG PET/CT bone/bone marrow findings in Hodgkin’s lymphoma may circumvent the use of bone marrow trephine biopsy at diagnosis staging显示文摘 | Gerard Moulin-Romsee Elif Hindié Xavier Cuenca Pauline Brice Didier Decaudin Myriam Bénamor Josette Brière Marcela Anitei Jean-Emmanuel Filmont David Sibon Eric Kerviler Jean-Luc Moretti | 2010 | European Journal of Nuclear Medicine and Molecular Imaging2010，，6： | 1 |
| 12 | Translocator protein (18<ce:hsp sp='0.25'/>kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function显示文摘 | Vassilios Papadopoulos Mario Baraldi Tomás R. Guilarte Thomas B. Knudsen Jean-Jacques Lacapère Peter Lindemann Michael D. Norenberg David Nutt Abraham Weizman Ming-Rong Zhang Moshe Gavish | 2006 | Trends in Pharmacological Sciences2006，，8： | 1 |
| 13 | Chlamydia antibodies, chlamydia heat shock protein, and adverse Sequelae after pelvic inflammatory disease: the PID evaluation and clinical health (PEACH) study 显示文摘 | Roberta NB David SE Holly RE | 2008 | Sexually Transmitted Diseases2008，35，： | 1 |
| 14 | The ecological limits of hydrologic alteration (ELOHA): a new framework for developing regional environmental flow standards显示文摘 | N. LEROYPOFF BRIAN D.RICHTER ANGELA H.ARTHINGTON STUART E.BUNN ROBERT J.NAIMAN ELOISEKENDY MIKEACREMAN COLINAPSE BRIAN P.BLEDSOE MARY C.FREEMAN JAMESHENRIKSEN ROBERT B.JACOBSON JONATHAN G.KENNEN DAVID M.MERRITT JAY H.O’KEEFFE JULIAN D.OLDEN KEVINROGERS RE | 2009 | Freshwater Biology2009，，1： | 1 |
| 15 | Design and function of novel superplasticizers for more durable high performance concrete (superplast project)显示文摘 | Yves F. Houst Paul Bowen Fran?ois Perche Annika Kauppi Pascal Borget Laurent Galmiche Jean-Fran?ois Le Meins Fran?oise Lafuma Robert J. Flatt Irene Schober Phil F.G. Banfill David S. Swift Bernt O. Myrvold Berit G. Petersen K?re Reknes | 2008 | Cement and Concrete Research2008，，10： | 1 |
| 16 | Quantitative detection of human immunodeficiency virus type 1 (HIV-1) viral load by SYBR green real-time RT-PCR technique in HIV-1 seropositive patients显示文摘 | Davide Gibellini Francesca Vitone Elisa Gori Michele La Placa Maria Carla Re | 2003 | Journal of Virological Methods2003，，2： | 1 |
| 17 | Statistical designs and response surface techniques for the optimization of chrom-atographic systems显示文摘 | Ferreira SL Bruns RE David JM | 2007 | J Chromatogr A2007，1158，12： | 1 |
| 18 | HIV-1 and HCV detection in dried blood spots by SYBR Green multiplex real-time RT-PCR显示文摘 | Elisa De Crignis Maria Carla Re Laura Cimatti Lisa Zecchi Davide Gibellini | 2010 | Journal of Virological Methods2010，，1： | 1 |
| 19 | Plants,selenium and human health显示文摘 | Danielle RE David ES | 2003 | Curr Opin Plant Biol2003，6，： | 1 |
| 20 | HIV-1 subtype C transmission network: The phylogenetic reconstruction strongly supports the epidemiological data显示文摘 | Isabella Bon Massimo Ciccozzi Gianni Zehender Carlo Biagetti Gabriella Verrucchi Alessia Lai Alessandra Lo Presti Davide Gibellini Maria Carla Re | 2010 | Journal of Clinical Virology2010，，： | 1 |
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