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| 1 | Two quantitative trait loci, Dw1 and Dw2, are primarily responsible for rootstock-induced dwarfing in apple显示文摘The apple dwarfing rootstock‘Malling9’(‘M9’)has been used worldwide both to reduce scion vigour and as a genetic source for breeding new rootstocks.Progeny of‘M9’segregate for rootstock-induced dwarfing of the scion,indicating that this trait is controlled by one or more genetic factors.A quantitative trait locus(QTL)analysis of a rootstock population derived from the cross between‘M9’בRobusta5’(non-dwarfing)and grafted with‘Braeburn’scions identified a major QTL(Dw1)on linkage group(LG)5,which exhibits a significant influence on dwarfing of the scion.A smaller-effect QTL affecting dwarfing(Dw2)was identified on LG11,and four minor-effect QTLs were found on LG6,LG9,LG10 and LG12.Phenotypic analysis indicates that the combination of Dw1 and Dw2 has the strongest influence on rootstock-induced dwarfing,and that Dw1 has a stronger effect than Dw2.Genetic markers linked to Dw1 and Dw2 were screened over 41 rootstock accessions that confer a range of effects on scion growth.The majority of the dwarfing and semi-dwarfing rootstock accessions screened carried marker alleles linked to Dw1 and Dw2.This suggests that most apple dwarfing rootstocks have been derived from the same genetic source. | Toshi M Foster Jean-Marc Celton David Chagné D Stuart Tustin Susan E Gardiner | 2015 | Horticulture Research2015，2，1： | 10 |
| 2 | Total pancreatectomy and islet autotransplantation: A decade nationwide analysis显示文摘AIM: To investigate outcomes and predictors of inhospital morbidity and mortality after total pancreatectomy(TP) and islet autotransplantation. METHODS: The nationwide inpatient sample(NIS) database was used to identify patients who underwent TP and islet autotransplantation(IAT) between 2002-2012 in the United States. Variables of interest were inherent variables of NIS database which included demographic data(age, sex, and race), comorbidities(such as diabetes mellitus, hypertension, and deficiency anemia), and admission type(elective vs nonelective). The primary endpoints were mortality and postoperative complications according to the ICD-9 diagnosis codes which were reported as the second to 25 th diagnosis of patients in the database. Risk adjusted analysis was performed to investigate morbidity predictors. Multivariate regression analysis was used to identify predictors of in-hospital morbidity.RESULTS: We evaluated a total of 923 patients who underwent IAT after pancreatectomy during 2002-2012. Among them, there were 754 patients who had TP + IAT. The most common indication ofsurgery was chronic pancreatitis(86%) followed by acute pancreatitis(12%). The number of patients undergoing TP + IAT annually significantly increased during the 11 years of study from 53 cases in 2002 to 155 cases in 2012. Overall mortality and morbidity of patients were 0% and 57.8 %, respectively. Postsurgical hypoinsulinemia was reported in 42.3% of patients, indicating that 57.7% of patients were insulin independent during hospitalization. Predictors of inhospital morbidity were obesity [adjusted odds ratio(AOR): 3.02, P = 0.01], fluid and electrolyte disorders(AOR: 2.71, P < 0.01), alcohol abuse(AOR: 2.63, P < 0.01), and weight loss(AOR: 2.43, P < 0.01). CONCLUSION: TP + IAT is a safe procedure with no mortality, acceptable morbidity, and achieved high rate of early insulin independence. Obesity is the most significant predictor of in-hospital morbidity. | Reza Fazlalizadeh Zhobin Moghadamyeghaneh Aram N Demirjian David K Imagawa Clarence E Foster Jonathan R Lakey Michael J Stamos Hirohito Ichii | 2016 | World Journal of Transplantation2016，6，1： | 9 |
| 3 | 大鼠中央杏仁核5-HT_3受体参与胸腺功能调制(英文)显示文摘本研究旨在探讨大鼠中央杏仁核(central amygdala,CeA)内5-HT3受体激动之后,对丝裂原刀豆球蛋白A(concanavalin A,ConA)刺激的胸腺细胞增殖反应的影响,及其潜在的神经内分泌调节环路。分别经大鼠腹腔(intraperitoneal,i.p.)、双侧侧脑室(intracerebroventricle,i.c.v.)和双侧CeA(intracentral amygdala,i.c.a.)注射选择性5-HT3受体激动剂1-phenylbiguanide(PBG),同时制备正常大鼠胸腺细胞悬液与不同浓度FBG(1×10-8~1×10-5mol/L)体外共同孵育。经MTT法测定显示,无论有无ConA刺激,正常大鼠离体胸腺细胞在与PBG(1×10-8~1×10-5mol/L)体外共同孵育时其增殖反应均不受后者影响;PBG i.p.(每天0.5 mg/kg,连续5 d)对ConA刺激的胸腺细胞的增殖反应亦无影响,而PBG i.c.v.(每天10μg/侧,连续5 d)则显著增强之;当PBG i.c.a.(每天1.0μg,侧,1 d或连续3、5、7 d)时,ConA刺激的胸腺细胞的增殖反应于给药后第1天即开始增强且日益显著,第5天达到高峰,第7天则趋于减弱。在给予PBG 5 min前相同给药部位先给予5-HT3受体拮抗剂tropisetron(TRP)预处理可逆转PBG的促胸腺细胞增殖效应。免疫组织化学SABC法检测显示,PBG(1.0μg/侧,i.c.a.)单次给药后各脑区可相继出现大量c-Fos阳性细胞(CeA:1 h;海马及皮层:1~2 h;下丘脑:4 h;中脑导水管周围灰质:8 h),并迅速达到各自高峰(CeA: 1 h;海马及皮层:2 h;下丘脑:4 h),与相应的生理盐水对照组及TRP预处理组相比均有显著性差异。随后,这一表达在各脑区中逐步减弱并消失(CeA:4 h;海马、皮层及下丘脑:8 h)。由此推论,大鼠CeA内5-HT3受体至少可部分通过边缘系统-皮层-下丘脑-中脑导水管周围灰质这一神经内分泌环路调制胸腺细胞功能。 | 徐民 陈伟强 王基平 David JR Foster 许德义 | 2007 | 生理学报2007，59，1： | 3 |
| 4 | Immediate Changes in Intraocular Pressure after Laser Peripheral Iridotomy in Primary Angle-Closure Suspects显示文摘 | Yuzhen Jiang Dolly S. Chang Paul J. Foster Mingguang He Shengsong Huang Tin Aung David S. Friedman | 2012 | Ophthalmology2012，，2： | 2 |
| 5 | Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study显示文摘 | Quan Dong Nguyen Syed Mahmood Shah Afsheen A. Khwaja Roomasa Channa Elham Hatef Diana V. Do David Boyer Jeffery S. Heier Prema Abraham Allen B. Thach Eugene S. Lit Bradley S. Foster Erik Kruger Pravin Dugel Thomas Chang Arup Das Thomas A. Ciulla John S. P | 2010 | Ophthalmology2010，，11： | 2 |
| 6 | The Association between Time Spent Outdoors and Myopia in Children and Adolescents显示文摘 | Justin C. Sherwin Mark H. Reacher Ruth H. Keogh Anthony P. Khawaja David A. Mackey Paul J. Foster | 2012 | Ophthalmology2012，，10： | 2 |
| 7 | Solution structure of the first three zinc fingers of TFIIIA bound to the cognate DNA sequence: determinants of affinity and sequence specificity 1 1 Edited by F.E.Cohen显示文摘 | Deborah S. Wuttke Mark P. Foster David A. Case Joel M. Gottesfeld Peter E. Wright | 1997 | Journal of Molecular Biology1997，，1： | 1 |
| 8 | Imports, exports, knowledge spillovers and growth 显示文摘 | Rod Falvey Neil Foster David Greenaway | 2004 | Economics Letters2004，85，： | 1 |
| 9 | Extracellular Matrix-Associated Serine Protease Inhibitors ( M r 33,000, 31,000, and 27,000) Are Single-Gene Products with Differential Glycosylation: cDNA Cloning of the 33-kDa Inhibitor Reveals Its Identity to Tissue Factor Pathway Inhibitor-2显示文摘 | C.N. Rao Prasad Reddy Yueying Liu Edel O’toole Dennis Reeder Donald C. Foster Walter Kisiel David T. Woodley | 1996 | Archives of Biochemistry and Biophysics1996，，1： | 1 |
| 10 | Northsouth trade,knowledge spillovers and growth 显示文摘 | Falvey Rod Nell Foster David Greenaway | 2002 | Journal of Economic Integration2002，17，： | 1 |
| 11 | Imports, exports,knowledge spillovers and growth显示文摘 | Falvey Rod Nell Foster David Greenaway | 2004 | Economics Letters2004，85，： | 1 |
| 12 | North - South Trade, Knowledge Spillovers and Growth 显示文摘 | Flavey Rod Foster David Greenaway | 2001 | Journal of Economic Integration2001，，17： | 1 |
| 13 | Using HOLSAT to evaluate tourist satisfaction at destinations: The case of Australian holidaymakers in Vietnam显示文摘 | Thuy-Huong Truong David Foster | 2005 | Tourism Management2005，，5： | 1 |
| 14 | Angle closure and angle‐closure glaucoma: what we are doing now and what we will be doing in the future显示文摘 | David S Friedman Paul J Foster Tin Aung Mingguang He | 2012 | Clinical & Experimental Ophthalmology2012，，4： | 1 |
| 15 | A systematic review and meta-analysis of studies using the STRATIFY tool for prediction of falls in hospital patients显示文摘 | David Oliver Alexandra Papatoannou Lora Giangregorio Lehana Thabane Katerina Reiagys Gary Foster | 2008 | Age and Ageing2008，37，： | 1 |
| 16 | Pulmonary insufficiency is the nexus of late complications in tetralogy of Fallot显示文摘 | David Gregg Elyse Foster | 2007 | Current Cardiology Reports2007，，4： | 1 |
| 17 | Phosphatidic acid and lipid-sensing by mTOR显示文摘 | David A. Foster | 2013 | Trends in Endocrinology & Metabolism2013，，6： | 1 |
| 18 | Soil carbon and nitrogen in a pine-oak sand plain in central Massachusetts: Role of vegetation and land-use history显示文摘 | Jana E. Compton Richard D. Boone Glenn Motzkin David R. Foster | 1998 | Oecologia1998，，4： | 1 |
| 19 | Frenetic显示文摘 | Nate Foster Rob Harrison Michael J. Freedman Christopher Monsanto Jennifer Rexford Alec Story David Walker | 2011 | ACM SIGPLAN Notices2011，，： | 1 |
| 20 | Intellectual Property Rights and Economic Growth 显示文摘 | Rod Falvey Neil Foster David Greenaway | 2004 | Internationalisation of Economic Policy Research Paper2004，，12： | 1 |
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