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| 1 | The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition显示文摘在人的不孕病人的精子在场的最普通的损害之一是精子鸡蛋识别的自发的失败。尽管这个唯一的细胞的相互作用现在能被象 intracytoplasmic 精子注射(ICSI ) 那样的帮助繁殖策略乐意地绕过,最近的大规模流行病学的研究鼓励了这种技术的小心的使用并且为对为有缺点的精子鸡蛋识别负责的机制的进一步的研究加亮需要。这个领域里的以前的工作证实了为卵母细胞相互作用负责的精子领域在动态地在女繁殖的道在 epididymal 成熟和 capacitation 期间被修改以前在精子发生期间被形成。当为这些顺序的 maturational 事件的规定负责的因素无疑是复杂的时,新兴的研究识别了分子的女伴,加热吃惊蛋白质 A2 (HSPA2 ) ,,在人的精子的这些事件的一个关键管理者。HSPA2 是支持合拢,运输,和集会蛋白质建筑群的 70 kDa 热吃惊蛋白质家庭的一个充实睾丸的成员并且断然被相关与在 vitro 授精(IVF ) 成功。而且,从人的精子 proteome 减少了 HSPA2 的表示为跟随 IVF 和 ICSI 的积云矩阵疏开,精子鸡蛋识别和授精导致一个损害能力。在这评论,我们考虑在精子功能支持 HSPA2 的角色的证据并且探索它被在不肥沃的病人的精子弄空的潜在的机制。进管理精子的分子的机制的如此的信息提议小说卓见工作。 | Brett Nixon Elizabeth G Bromfield Matthew D Dun Kate A Redgrove Eileen A McLaughlin R John Aitken | 2015 | Asian Journal of Andrology2015，17，4： | 8 |
| 2 | Bay of island and Little Port complexes, revisited: Age, geochemical and isotopic evidence confirm supra-subduction zone origin显示文摘 | JNNER G A DUNNING G R MALAPS J | 1991 | Can J Geol Soc London1991，28，： | 1 |
| 3 | Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats显示文摘 | Mouravlev A Dunning J Young D | 2006 | Proc Natl Acad SCI USA2006，103，12： | 1 |
| 4 | Azithromycin for the secondary prevention of coronary heart disease events:The WIZARD study:a randomized controlled trial显示文摘 | O'Con nor CM Dun ne M W Pfeffer M A | | 0，，： | 1 |
| 5 | Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology 显示文摘 | Reiter R J Dun XT Korkmaz A | 2014 | Hum Reprod Update2014，20，2： | 1 |
| 6 | DNA repair polymorphisms and cancer risk in non-smokers in a cohort study显示文摘 | Matullo G Dunning A M Guarrera S | 2006 | Carcinogenesis2006，27，5： | 1 |
| 7 | The patched polymorphism Pro1315Leu (C3944T)may modulate the association between use of oral contraceptives and breast cancer risk显示文摘 | Chang-Claude J Dunning A Schnitzbauer U | 2003 | Int J Cancer2003，103，6： | 1 |
| 8 | Wealth Effects of Convertible Bond and Convertible Preference Share Issues: An Empirical Analysis of the UK Market 显示文摘 | Abhyankar A Dunning A | 1999 | Journal of Banking and Finance1999，23，7： | 1 |
| 9 | Superparamagnetic iron oxide-labeled schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplanta- tion into the CNS 显示文摘 | Dunning MD Lakatos A Loizou L | 2004 | J Neurosci2004，24，44： | 1 |
| 10 | The influence of Hymer's dissertation on the theory of foreign direct investment 显示文摘 | Dunning J H Rugman A M | 1985 | The Ameri- can Economic Review1985，75，2： | 1 |
| 11 | Some in vivo effects of localized nuclear disintegration products on a transplantable mouse sarcoma显示文摘 | ZAHL P A COOPER F S DUNNING J R | 1940 | Ptoc Natl Acad Sci1940，26，： | 1 |
| 12 | Does prophylactic tranexamic acidsafetly reduce bleelding without increasing thrombotic complications in patientsundergoing cardiac surgery显示文摘 | Thiagarajamurthy S Levine A Dunning J | 2004 | Interat Cardiovasc Thorac Surg2004，3，3： | 1 |
| 13 | Branching genes are conserved across species, genes controlling a novel signal in pea are coregulated by other long-distance signals显示文摘 | Johnson X Brcich T Dun E A | 2006 | Plant physiology2006，142，12： | 1 |
| 14 | Superparamagnetic iron oxide-labeled schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS显示文摘 | Dunning MD Lakatos A Loizou L | 2004 | J Neurosci2004，24，： | 1 |
| 15 | The extent of linkage disequilibrium in four populations with distinct demographic histories显示文摘 | Dunning A M Durocher F Healey C S | 2000 | Am J Hum Genet2000，67，6： | 1 |
| 16 | The influence of Hymer' s dissertation on the theory of foreign direct investment 显示文摘 | Dunning J H Rugman A M | 1985 | American Economic Review1985，75，2： | 1 |
| 17 | A common coding variant in CASP8 is associated with breast cancer risk 显示文摘 | Cox A Dunning AM Garcia-Closas M | 2007 | Nat Geuet2007，39，3： | 1 |
| 18 | Is thymectomy in non-thymomatousmyasthenia gravis of any benefit显示文摘 | Diaz A Black E Dunning J | 2014 | Interact Cardiovasc Thorac Surg2014，18，3： | 1 |
| 19 | Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells显示文摘 | DODDRELL R D DUN X P SHIVANE A | 2013 | Brain2013，136，2： | 1 |
| 20 | The patched polymorphism PRO1315LEU (C3944T) may modulate the association between use of oral contraceptives and breast cancer risk 显示文摘 | J Chang-Claude Dunning A and Schnitzbauer U | 2002 | Int J Cancer2002，，103： | 1 |
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