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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Temporal aggregation of GARCH process显示文摘 | Drost F Nijmab T E | 1993 | Econometrics1993，61，： | 1 |
| 3 | Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin显示文摘 | Evers B Drost R Schut E | 2008 | Clin Cancer Res2008，14，12： | 1 |
| 4 | Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin显示文摘 | Evers B Drost R Schut E | 2008 | Clin Cancer Res2008，14，12： | 1 |
| 5 | Oxidative stress and airway inflammation in severe exacerbations of COPD显示文摘 | DROST E M SKWARSKI K M SAULEDA J | 2005 | Thorax2005，60，： | 1 |
| 6 | transcranial Doppler study of blood flow velocity in the middle cerebral arteries performed at rest and during mental activities显示文摘 | Droste DW Harders AG Rastogi E | 1989 | Stroke1989，20，： | 1 |
| 7 | Oxidative stress and airway inflammation in severe exacerbations of COPD显示文摘 | E M Drost K M Skwarski J Sauleda | 2005 | Thorax2005，60，： | 1 |
| 8 | Two transeranial Doppler studies on blood flow velocity in both middle cerebral arteries during rest and the performance of cognitive tasks显示文摘 | Droste DW Harders AG Rastogi E | 1989 | Neuropsychology1989，27，10： | 1 |
| 9 | Two transcranial Doppler studies on blood flow velocity in both middle cerebral arteries during rest and the performance of cognitive tasks显示文摘 | Droste DW Harders AG Rastogi E | 1989 | Neuropsychologia1989，27，： | 1 |
| 10 | Temporal aggregation of GARCH processes显示文摘 | Nijiman T E | 1993 | Econometrica1993，64，4： | 1 |
| 11 | Potential role of IL-8 ,platelet-acti- rating factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion re- ceptor expression, and chemotaxis显示文摘 | DROST E M MACNEE W | 2002 | Eur J Immunol2002，32，2： | 1 |
| 12 | Temperature responsive colloidal particles from non-covalently interacting small molecular weight natural bioactive molecules显示文摘 | Patel AR Drost E Den Adel R | 2012 | Soft Matter2012，8，13： | 1 |
| 13 | Heteropolymetalate Clusters of theSubvalent Main Group Elements BiⅢ and SbⅢ显示文摘 | Loose I Droste E B(o)sing M Pohlmann H. Dickman M.H. Rosu C. Pope M.T. Krebs B | | 0，，： | 1 |
| 14 | Estimation and testing in models containing both jump and conditional hetcroskedasticity显示文摘 | Drost F C Nijman T E Werker B J M | 1998 | Journal of Business and Economic Statistics1998，16，2： | 1 |
| 15 | Selective inhibition of BRCA2de-ficient mammary tumor cell growth by AZD2281and cisplatin显示文摘 | Evers B Drost R Schut E | 2008 | Clin Cancer Res2008，14，3： | 1 |
| 16 | Heteropolymetalate clusters of the subvalent main group elements BiⅢ and SbⅢ显示文摘 | LOOSE I DROSTE E BOSING M | | 0，，： | 1 |
| 17 | 显示文摘 | Parmentier M Drost E Hirani N | 1999 | Am J Respir Crit Care Med1999，159，： | 1 |
| 18 | Susceptibility of Brazilian soybean cultivars to Agrobacterium tumefaciens 显示文摘 | Droste A Bodanesc-Zanettini M H Mundstock E | 1994 | Rev Brail Genet1994，17，： | 1 |
| 19 | Novel Keggin stannato(Ⅱ)tungstates with lone-pair assembling atoms:syntheses,crystal structure and spectroscopic studies显示文摘 | KREBS B DROSTE E PIEPENBRINK M | 2000 | C R Acad Sci Ser Ⅱc Chim2000，，： | 1 |
| 20 | Thiol antioxidants inhihitneutro Phil chem otaxis by deereasing release of IL-8 from maerophages and pulmonary epthelial cells(abstraet)显示文摘 | Parmentier M Drost E Hirani N | 1999 | Am J Respire Crit Care Med1999，159，1： | 1 |
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