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| 1 | Helicobacter pylori CagA and VacA genotypes and gastric phenotype: a meta-analysis显示文摘 | Joana I. Matos Henrique A.C. de Sousa Ricardo Marcos-Pinto Mário Dinis-Ribeiro | 2013 | European Journal of Gastroenterology & Hepatology2013,,12: | 3 |
| 2 | Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia显示文摘 | Francielle Tramontini Gomes de Sousa Cardozo Carla Maísa Camelini Alessandra Mascarello Márcio José Rossi Ricardo José Nunes Célia Regina Monte Barardi Margarida Matos de Mendon?a Cláudia Maria Oliveira Sim?es | 2011 | Antiviral Research2011,,1: | 2 |
| 3 | Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy显示文摘AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy(eUBM)to track the progression of mouse colonic lesions.METHODS:Ten mice were treated with a single azoxy-methane intraperitoneal injection(week 1)followed by seven days of a dextran sulfate sodium treatment in their drinking water(week 2)to induce inflammationassociated colon tumors.eUBM was performed simultaneously with colonoscopy at weeks 13,17-20 and21.A 3.6-F diameter 40 MHz mini-probe catheter was used for eUBM imaging.The ultrasound mini-probe catheter was inserted into the accessory channel of a pediatric flexible bronchofiberscope,allowing simultaneous acquisition of colonoscopic and eUBM images.During image acquisition,the mice were anesthetized with isoflurane and kept in a supine position over a stainless steel heated surgical waterbed at 37℃.Both eUBM and colonoscopic images were captured and stored when a lesion was detected by colonoscopy or when the eUBM image revealed a modified colon wall anatomy.During the procedure,the colon was irrigated with water that was injected through a flush port on the mini-probe catheter and that acted as the ultrasound coupling medium between the transducer and the colon wall.Once the acquisition of the last eUBM/colonoscopy section for each animal was completed,the colons were fixed,paraffin-embedded,and stained with hematoxylin and eosin.Colon images acquired at the first time-point for each mouse were compared with subsequent eUBM/colonoscopic images of the same sites obtained in the following acquisitions to evaluate lesion progression.RESULTS:All 10 mice had eUBM and colonoscopic images acquired at week 13(the first time-point).Two animals died immediately after the first imaging acquisition and,consequently,only 8 mice were subjected to the second eUBM/colonoscopy imaging acquisition(at the second time-point).Due to the advanced stage of colonic tumorigenesis,5 animals died after the second time-point image acquisition,and thus,only three were subjected to the third eUBM/colonoscopy imaging acquisition(the third time-point).eUBM was able to detect the four layers in healthy segments of colon:the mucosa(the first hyperechoic layer moving away from the mini-probe axis),followed by the muscularis mucosae(hypoechoic),the submucosa(the second hyperechoic layer)and the muscularis externa(the second hypoechoic layer).Hypoechoic regions between the mucosa and the muscularis externa layers represented lymphoid infiltrates,as confirmed by the corresponding histological images.Pedunculated tumors were represented by hyperechoic masses in the mucosa layer.Among the lesions that decreased in size between the first and third time-points,one of the lesions changed from a mucosal hyperplasia with ulceration at the top to a mucosal hyperplasia with lymphoid infiltrate and,finally,to small signs of mucosal hyperplasia and lymphoid infiltrate.In this case,while lesion regression and modification were observable in the eUBM images,colonoscopy was only able to detect the lesion at the first and second time-points,without the capacity to demonstrate the presence of lymphoid infiltrate.Regarding the lesions that increased in size,one of them started as a small elevation in the mucosa layer and progressed to a pedunculated tumor.In this case,while eUBM imaging revealed the lesion at the first time-point,colonoscopy was only able to detect it at the second time-point.All colonic lesions(tumors,lymphoid infiltrate and mucosal thickening)were identified by eUBM,while colonoscopy identified just76%of them.Colonoscopy identified all of the colonic tumors but failed to diagnose lymphoid infiltrates and increased mucosal thickness and failed to differentiate lymphoid infiltrates from small adenomas.During the observation period,most of the lesions(approximately67%)increased in size,approximately 14%remained unchanged,and 19%regressed.CONCLUSION:Combining eUBM with colonoscopy improves the diagnosis and the follow-up of mouse colonic lesions,adding transmural assessment of the bowel wall. | Rossana C Soletti Kelly Z Alves Marcelo AP de Britto Dyanna G de Matos Mnica Soldan Helena L Borges Joo C Machado | 2013 | World Journal of Gastroenterology2013,19,44: | 1 |
| 4 | Exercise training restores baroreflex sensitivity in never-treated hypertensive patients显示文摘 | LATERZA M C DE MATOS L D TROMBETTA I C | 2007 | Hypertension2007,49,6: | 1 |
| 5 | S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial显示文摘 | Mato]M Camara] Fernandez de Paz] | 1999 | J Hepatol1999,30,6: | 1 |
| 6 | Trypsininhibitor from Dimorphandra mollis seeds: purification andproperties显示文摘 | Macedo M L de Matos D G Manhado 0 L | 2000 | Phytochemistry2000,54,6: | 1 |
| 7 | The northeast Brazilian rift system 显示文摘 | Renato M Darros de Matos | 1992 | Tectonics1992,11,4: | 1 |
| 8 | Crack tip deformation -elds and fatigue crack growth rates in Ti-6Al-4V显示文摘 | KORSUNSKY A M SONG X BELNOUE J JUN T HOFMANN F DE MATOS P F P NOWELL D DINI D APRICIO-BLANCO O WALSH M J | 2009 | International Journal of Fatigue2009,31,1112: | 1 |
| 9 | An overview on fatigue analysis of aeronautical structural details: open hole, single rivet lap-joint, and lap-joint panel显示文摘 | De Castro P M S T De Matos P F P Moreira P M G P | 2007 | Materials Science and Engineering: A2007,,: | 1 |
| 10 | A Comparison of the Fatigue Behavior between $355 and S690 Steel Grades 显示文摘 | DE JESUS A M P MATOS R FONTOURA B F C | 2012 | Journal of Constructional Steel Research2012,79,: | 1 |
| 11 | Stress intensity factor and load transfer analysis of a cracked riveted lap joint 显示文摘 | Moreira P M de Matos P F P Camanho P P | 2007 | Materials & Design2007,28,: | 1 |
| 12 | Modeling of Particle Formation from a Gas-Saturated Solution Processes 显示文摘 | Li J Rodrigues M Paiva A Matos HA Gomes de Azevedo E | 2005 | AIChE J2005,51,: | 1 |
| 13 | Micheal additions of primary and secondary amines to acrylonitrile catalyzed by lipases显示文摘 | de Souza Roma Matos L M C Goncalves K M | 2009 | TetrahedronLetters2009,50,: | 1 |
| 14 | Enhanced morbidity of pectoralis major myoeutaneous flap used for salvage after previously failed oncological treatment and un- successful reconstructive head and neck surgery显示文摘 | RIBEIRO SALLES VANNI (2 M DE MATOS L L FARO JUNIOR M P | 2012 | Scientific World Journal2012,2012,38: | 1 |
| 15 | An overview on fatigue analysis of aeronautical structural details:Open hole,single rivet lap-joint,and lap-joint panel显示文摘 | P M S T de Castro P FP de Matos P M G P Moreira | 2007 | Materials Science and Engineering:A2007,,: | 1 |
| 16 | 查看详情显示文摘 | B M Escher R L de Matos L Davidovich | | 0,,05: | 1 |
| 17 | Effects of a protected area on land-use dynamics and socioeco- nomic development of local populations 显示文摘 | Schmitz M F Matos D G G De Aranzabal I | 2012 | Biological Conserva- tion2012,149,1: | 1 |
| 18 | Immunoexpression of TNF-αand TGF-βin central and peripheral giant cell lesions of the jaws显示文摘 | de Matos FR de Moraes M Nonaka CF | 2012 | J Oral Pathol Med2012,41,2: | 1 |
| 19 | ChEBI: a database and ontology for chemical entities of biological interest显示文摘 | Degtyarenko K de Matos P Ennis M | 2008 | Nucleic Acids Res2008,36,: | 1 |
| 20 | Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy显示文摘 | Matos JP de Lourdes Rodrigues M Ismerim VL | 2005 | Clin Nephrol2005,64,3: | 1 |