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| 1 | Hepatocyte transplantation program:Lessons learned andfuture strategies显示文摘This review aims to share the lessons we learned over time during the setting of the hepatocyte transplantation(HT) program at the Hepatic Cell Therapy Unit at Hospital La Fe in Valencia. New sources of liver tissue for hepatocyte isolation have been explored. The hepatocyte isolation and cryopreservation procedures have been optimized and quality criteria for assessment of functionality of hepatocyte preparations and suitability for HT have been established. The results indicate that:(1) Only highly viable and functional hepatocytes allow to recover those functions lacking in the native liver;(2) Organs with steatosis(≥ 40%) and from elderly donors are declined since low hepatocyte yields, viability and cell survival after cryopreservation, are obtained;(3) Neonatal hepatocytes are cryopreserved without significant loss of viability or function representing high-quality cells to improve human HT;(4) Cryopreservation has the advantage of providing hepatocytes constantly available and of allowing the quality evaluation and suitability for transplantation; and(5) Our results from 5 adults with acute liver failure and 4 from children with inborn metabolic diseases, indicate that HT could be a veryuseful and safe cell therapy, as long as viable and metabolically functional human hepatocytes are used. | Eugenia Pareja Ibars Miriam Cortes Laia Tolosa Maria JoséGómez-Lechón Slivia López JoséVicente Castell JoséMir | 2016 | World Journal of Gastroenterology2016，22，2： | 3 |
| 2 | An integrated analysis of an orogen sedimentary basin pair: Latest Cretaceous-Cenozoic evolution of the linked Eastern Cordillera orogen and the Llanos foreland basin of Colombia显示文摘 | Bayona G Cortes M Jaramillo C | 2008 | GSA Bulletin2008，120，9： | 1 |
| 3 | In vitro and in vivo pharma- cological role of TLQP-21, a VGF-derived peptide, in the regulation of rat gastric motor functions显示文摘 | Severirti C La Corte G Improta G | 2009 | Pharmacol2009，157，： | 1 |
| 4 | Mapping 137Cs deposition: Data validation methods and data interpretation 显示文摘 | Dubois G De Cort M | 2001 | Journal of Environmental Radioactivity2001，53，3： | 1 |
| 5 | Mapping 137Cs deposition:data validation methods and data interpretation显示文摘 | DUBOIS G DE CORT M | 2001 | Journal of Environmental Radioactivity2001，53，3： | 1 |
| 6 | Correlation of the Tei index with invasive measurement of ventricular function in a porcine mode 显示文摘 | La Corte J C Cabreriza S E Rabk in D G | 2003 | Am soe Echocardiogr2003，16，5： | 1 |
| 7 | 显示文摘 | CORT(E)S-J(A)COME M A ESCOBAR J ANGELES CH(A)VEZ C LPEZ-SALINAS E ROMERO E FERRAT G TOLEDO-ANTONIO J A | 2008 | Catal Today2008，130，1： | 1 |
| 8 | An unusually large multifunctional polypeptide in the erythromycin- producing polyketide synthase of Saecharopolyspora erythraea显示文摘 | Cortes J Haydock S F Roberts G A | 1990 | Nature1990，348，： | 1 |
| 9 | Pilot study of SCH66336 (Lonafarnib),a farnesyl transferase inhibitor (FTI),in patients with chronic myeloid leukemia (CML) in chronic or accelerated phase resistant or refractory to imatinib显示文摘 | Cortes JE Daley G Talpaz M | 2002 | Blood2002，100，： | 1 |
| 10 | Phase 1 study of tipifamib in combination with imatinib forpatients with chronic myelogenous leukemia in chronic phaseafter imatinib failure显示文摘 | CORTES J QUINT'S-CARDAMA A GARCIA-MANERO G | 2007 | Cancer2007，110，9： | 1 |
| 11 | Efficacy and safety of intravenous voriconazole and intravenous itraconazole for antifungal prophylaxis in patients with acute myelogenous leukemia or high - risk myelodysplastic syndrome 显示文摘 | Mattiuzzi GN Cortes J Alvarado G | 2011 | Support Care Cancer2011，19，： | 1 |
| 12 | Twice-daily fludarabine and cytarabine combination with or without gentuzumab ozogamicin is effective in patients with relapsed/refractory acute myeloid leukemia, high-rlsk myelodysplastic syndrome, and blast- phase chronic myeloid leukemia 显示文摘 | Jabbour E Garcia-Manero G Cortes J | 2012 | Clin Lymphoma Myeloma Leuk2012，12，4： | 1 |
| 13 | An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea 显示文摘 | Cortes J Haydock S F Roberts G A | 1990 | Nature1990，348，6297： | 1 |
| 14 | Experimental evaluation of steel slit panel- frames for seismic resistance显示文摘 | Cortes G Liu J | 2011 | Journal of Constructional Steel Research2011，67，2： | 1 |
| 15 | Aortoesophageal fistula due to ingestion of button battery显示文摘 | BAEZA H C CORTES G R VELASCO S L | 2010 | Cir Pediatr2010，23，： | 1 |
| 16 | Measuring the Performance of Nations at the Summer Olympics using Data Envelopment Analysis 显示文摘 | Lozano S Villa G Guerrero F Cortes P | 2003 | Journal of the Operational Research Society2003，53，5： | 1 |
| 17 | Oxidative dehydrogenation of propane over calcined vanadate-exchanged Mg,Al-layered double hydroxides 显示文摘 | Bahranowskia K Bueno G Cortes C V | 1999 | Applied Catalysis A: General1999，185，1： | 1 |
| 18 | Development of a tyrosinase biosensor based on gold nanoparticles-modified glassy carbon electrodes application to the measurement of a bioelectroehemical polyphenols index in wines显示文摘 | SANZ V C MENA M L CORTES A G | 2005 | Anal China Acts2005，528，： | 1 |
| 19 | Elderly onset rheumatoid arthritis: clinical aspects显示文摘 | Bajocchi G La Corte R Loeaputo A | 2000 | Clin Exp Rheumatol2000，18，420： | 1 |
| 20 | Comparison of two standard test methods for determining explosion limits of gases at atmospheric conditions 显示文摘 | G De Smedt F de Corte R Notele | 1999 | Journal of Hazardous Materials1999，70，3： | 1 |
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