维普中文期刊产品整合服务
147篇 您的检索式:作者名="Cesar E"
    题名 作者 年代 出处 被引量
1Expression of HER2 and bradykinin B_1 receptors in precursor lesions of gallbladder carcinoma显示文摘AIM:To determine the expression of HER2 and bradykinin B 1 receptors(B 1 R) in the two pathogenic models of gallbladder cancer:the metaplasia-dysplasia-carcinoma and the adenoma-carcinoma pathways.METHODS:Receptor proteins were visualized by immunohistochemistry on 5-μm sections of paraffin-embedded tissue.Expression of both receptors was studied in biopsy samples from 92 patients(6 males and 86 females;age ranging from 28 to 86 years,mean 56 years).High HER2 expression in specimens was additionally investigated by fluorescence in situ hybridiza-tion.Cell proliferation in each sample was assessed by using the Ki-67 proliferation marker.RESULTS:HER2 receptor protein was absent in adenomas and in normal gallbladder epithelium.On the contrary,there was intense staining for HER2 on the basolateral membrane of epithelial cells of intestinal metaplasia(22/24;91.7%) and carcinoma in situ(9/10;90%),the lesions that displayed a significantly high proliferation index.Protein up-regulation of HER2 in the epithelium with metaplasia or carcinoma in situ was not accompanied by HER2 gene amplification.A similar result was observed in invasive carcinomas(0/12).The B 1 R distribution pattern mirrored that of HER2 except that B 1 R was additionally observed in the adenomas.The B 1 R appeared either as cytoplasmic dots or labeling on the apical cell membrane of the cells composing the epithelia with intestinal metaplasia(24/24;100%) and carcinoma in situ(10/10;100%) and in the epithelial cells of adenomas.In contrast,both HER2(4/12;33%) and B 1 R(1/12;8.3%) showed a low expression in invasive gallbladder carcinomas.CONCLUSION:The up-regulation of HER2 and B1R in precursor lesions of gallbladder carcinoma suggests cross-talk between these two receptors that may be of importance in the modulation of cell proliferation in gallbladder carcinogenesis.Cesar Toledo Carola E Matus Ximena Barraza Pamela Arroyo Pamela Ehrenfeld Carlos D Figueroa Kanti D Bhoola Maeva del Pozo Maria T Poblete 2012World Journal of Gastroenterology2012,18,11:6
2Profiling Peruvian Consumers' Lifestyles, Market Seg-mentation, and Ethnocentrism显示文摘Spillan John E Kucukeiniroglu Orsay de Mayolo Cesar Antunez 2007Latin American Business Review2007,,8:1
3Estimating and modeling space-time correlation structures显示文摘De Cesare L Myers D E Posa D 2001Statistics &Probability Letters2001,51,1:1
4Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty显示文摘Di Cesare PE Chang E Preston CF 2005J Bone Joint Surg Am2005,87,9:1
5Soluble CD30 serum levels before and after treatment with alpha-interferon in patients with chronic hepatitis C 显示文摘Di Cesare E Spadaro A Ajello A 2005Clin Chem Lab Med2005,43,8:1
6The use of lidocaine as an anti-inflammatory substance: A systematic review显示文摘Hugo Cesar Pinto Marques Caracas José Vinícius Bolognesi Maciel Patrícia Machado Rodrigues e Silva Martins Margareth Maria Gomes de Souza Lucianne Cople Maia 2008Journal of Dentistry2008,,2:1
7Serum interleukin-6 as a marker of periprosthetic infection following total hip and knee arthroplasty显示文摘Di Cesare PE Chang E Preston CF 2005J Bone Joint Surg Am2005,87,9:1
8Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines显示文摘Perego P Coma E De Cesare MD 2001Curr Med Chem2001,8,1:1
9Antidepres- sant-like effect of artemin in mice: A mechanism for acetyl-L: - carnitine activity on depression 显示文摘Di Cesare Mannelli L Vivoli E Salvicchi A 2011Psychopharmacology2011,218,2:1
10Comparatve evaluation of TEE,Conventional MRI and contrast enhance 3D breath-hold MRA in the post-operative follow-up of dissecting aneurysms显示文摘CESARE E D GIORDANO A V CERONE G 2000Int J Card Imaging2000,16,:1
11Serum interleu- kin -6 as a marker of periprosthetic infection following to- tal hip and knee arthroplasty显示文摘Di Cesare PE Chang E Preston CF 2005J Bone Joint Surg(Am)2005,87,9:1
12Electronic nose and SPME techniques to monitor phenanthrene biodegradation in soil显示文摘De Cesare F Pantalei S Zampetti E 2008Sensors and Actuators B:Chemical2008,131,1:1
13Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors 显示文摘Souslova V Cesare E Ding Y 2000Nature2000,407,:1
14MRI characterization of residual mediastinal masses in Hodgkin's disease: long-term follow-up显示文摘Di Cesare E Cerone G Enrici RM 2004Magn Reson Imaging2004,22,:1
15Relationship between follicle size and ultrasound-guided transvaginal oocyte recovery显示文摘MARCELO M S CESAR R E JOAQUIM M G etal 2001Anim Reprod Sci2001,67,:1
16Reli- able teleportation in trappedions显示文摘Solano E Cesar C L de Matos Filho R L 2001European Physi- cal Journal D2001,13,1:1
17Prevention and control of cystic echinococcosis显示文摘Philip S Craig Donald P McManus Marshall W Lightowlers Jose A Chabalgoity Hector H Garcia Cesar M Gavidia Robert H Gilman Armando E Gonzalez Myriam Lorca Cesar Naquira Alberto Nieto Peter M Schantz 2007The Lancet Infectious Diseases2007,,6:1
18Gastric adenocarcinoma:magnetic resonance versus surgical staging显示文摘Costanzi A Di Cesare E Guadagni S 1996Radiol Med (Torino)1996,92,:1
19Physical origin of mode instabilities in high power fiber laser system显示文摘Cesar J Tino E Hans J O 2012Optics Express2012,20,12:1
20Mutations in the kinaseRsk-2 associated with Coffin-Lowry syndrome 显示文摘Trivier E De Cesare D Jacquot S 1996Nature1996,384,6609:1
返回顶部 每页显示:
共8页 首页 上一页 第1页 下一页 末页 /8 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费