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| 1 | The direction of causality between financial development and economic growth显示文摘 | César Calderón Lin Liu | 2003 | Journal of Development Economics2003，，1： | 3 |
| 2 | Preoperative immunonutrition in patients undergoing liver resection:A prospective randomized trial显示文摘BACKGROUND Preoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.AIM To evaluate the effects of preoperative nutritional supplementation enriched with arginine and n-3 fatty acids on inflammatory and immunologic markers and clinical outcome in patients undergoing liver resection.METHODS Thirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact? [1020 kcal/d, immunonutrition(IMN) group], or standard care [no supplementation, standard care(STD) group]. Nutritional status was measured at study entry by subjective global assessment(SGA).Functional assessments(grip strength, fatigue and performance status) were carried out at study entry, on the day prior to surgery, and on postoperative day(POD) 7 and 30. Inflammatory and immune markers were measured at study entry, on the day prior to surgery, and POD 1, 3, 5, 7, 10 and 30. Postoperative complications were recorded prospectively until POD30.RESULTS A total of 32 patients(17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of(eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7(P < 0.05). Plasma interleukin(IL)-6 concentrations were elevated in the IMN group(P = 0.017 for POD7). No treatment effect was detected for functional measures, immune response(white cell count and total lymphocytes) or markers of inflammation(C-reactive protein,tumour necrosis factor-α, IL-8, IL-10). There were 10 patients with infectious complications in the IMN group and 4 in the STD group(P = 0.087). Median hospital stay was 9(range 4–49) d in the IMN group and 8(3-34) d in the STD group(P = 0.476).CONCLUSION In well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition. | Kylie Russell Han-Guang Zhang Lyn K GillANDers Adam SJR Bartlett Helena L Fisk Philip C Calder Peter J Swan Lindsay D Plank | 2019 | World Journal of Hepatology2019，11，3： | 3 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Cardiovascular effects of marine omega-3 fatty acids显示文摘 | Palaniappan Saravanan Neil C Davidson Erik B Schmidt Philip C Calder | 2010 | The Lancet2010，，9740： | 2 |
| 5 | Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale显示文摘 | CALDER P C | 2009 | Biochimie2009，91，6： | 1 |
| 6 | The effect of propolis and its components on eicosanoid production during the inflammatory response 显示文摘 | Mirzoeva O K Calder P C | 1996 | Prostaglandins Leukotrienes Essent Fatty Acids1996，55，6： | 1 |
| 7 | Evolution of FLASH, a multi-physics scientific simulation code for high-performance computing 显示文摘 | Dubey A Antypas K Calder A C | 2014 | International Journal of High Performance Computing Applications2014，28，2： | 1 |
| 8 | Fuel utilization by cells of the immune system 显示文摘 | Calder P C | 1995 | The Proceedings of Nutrition Society1995，54，1： | 1 |
| 9 | Olive oil in parenteral nutrition 显示文摘 | SALA-VILA BARBOSA V M CALDER P C et al | 2007 | Curr Opin Clin Nutr Metab Care2007，10，2： | 1 |
| 10 | Conversion of a - linolenic acid to longer- chain polyunsaturated fatty acids in human adults 显示文摘 | BURDGE G C CALDER P C | 2005 | Reprod Nutr Dev2005，45，5： | 1 |
| 11 | Glutamine and the immune system显示文摘 | Calder P C Yaqoob P | 1999 | Amino Acids1999，17，： | 1 |
| 12 | The proposed role of glutamine in some cells of the immune system and speculative consequences for the whole animal显示文摘 | NEWSHOLME E A CALDER P C | 1997 | Nutrition1997，13，78： | 1 |
| 13 | Glutamine and the immune system显示文摘 | Calder P C Yaqoob P | 1999 | Amino Acids1999，17，3： | 1 |
| 14 | Anxiety-Related Bias in the Classification of E- motionally Ambiguous Facial ExpressionsJ显示文摘 | RICHARDS A FRENCH C C CALDER A J | 2002 | Emo- tion2002，2，3： | 1 |
| 15 | Early nutrition and immunity-progress and perspectives 显示文摘 | CALDER P C KRAUSS-ETSCHMANN S DE JONG E C et al | 2006 | Br J Nutr2006，96，4： | 1 |
| 16 | Glutamine requirement of proliferating T-lymphocytes显示文摘 | YAGOOB P CALDER P C | 1997 | Nutrition1997，13，： | 1 |
| 17 | n -3 polyunsaturated fatty acids, inflammation, and inflammatory diseases 显示文摘 | CALDER P C | 2006 | Am J Clin Nutr2006，83，6： | 1 |
| 18 | In vitro transdermal delivery of the major catechins and caffeine from extract of Camellia sinensis显示文摘 | Batchelder R J Calder R J Thomas C P | 2004 | International Journal of Pharmaceutics2004，4551，： | 1 |
| 19 | Teachers developing assessments of early literacy : A community of practice project 显示文摘 | Perry N E Walton C & Calder K | 1999 | Teacher Education and Special Education1999，22，4： | 1 |
| 20 | Maternal plasma phosphatidylcholine fatty acids and atopy and wheeze in the offspring at age of 6 years显示文摘 | PIKE K C CALDER P C INSKIP H M | 2012 | Clin Dev Immunol2012，2012，47： | 1 |
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