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| 1 | FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle. | Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes | 2020 | Data Intelligence2020，2，1： | 26 |
| 2 | Preservation of platelet function in patients with cirrhosis and thrombocytopenia undergoing esophageal variceal ligation显示文摘Background:Thrombocytopenia is a possible risk factor for bleeding after band ligation of esophageal varices.However,elevated von Willebrand factor(VWF)in cirrhosis improves platelet function and could decrease this risk.Our objective was to assess platelet function in patients with cirrhosis undergoing esophageal variceal ligation(EVL).Methods:The assessment consisted of platelet count,antigen and activity of VWF and VWF-cleaving protease ADAMTS-13 activity,and a platelet adhesion and aggregation test simulating vascular flow in vivo(Impact-RR)prior to EVL.Results:Totally 111 patients were divided into three groups according to platelet count:(1)<50×109/L(n=38,34.2%);(2)50×109/L to 100×109/L(n=47,42.3%);and(3)>100×109/L(n=26,23.4%).No statistically significant difference was found in the aggregate size of platelets[group 1:41.0(31.8–67.3)μm 2;group 2:47.0(33.8–71.3)μm 2;and group 3:47.0(34.0–66.0)μm 2;P=0.60]and no significant correlation was found between aggregate size and platelet count(Spearman r=0.07;P=0.47).Surface coverage was 4.1%(2.8%–6.7%),8.5%(4.0%–10.0%),and 9.0%(7.1%–12.0%)(P<0.001)in groups 1,2 and 3,respectively and correlated with platelet count(Spearman r=0.39;P<0.0001).There was no significant difference between groups in VWF or ADAMTS-13.Post-EVL bleeding occurred in six(5.4%)patients(n=2 in group 1,n=1 in group 2,and n=3 in group 3;P=0.32).Patients with bleeding had higher MELD scores[15.0(11.3–20.3)versus 12.0(10.0–15.0);P=0.025],but no difference was demonstrated for platelet function parameters.Conclusion:Platelet function is preserved even in the presence of thrombocytopenia,including in the patients with post-EVL bleeding. | Evandro de Oliveira Souza Elbio Antonio D’Amico Tania Rubia Flores da Rocha Caroline Marcondes Ferreira Juliana Medeiros Batista Luiz Augusto CarneiroD’Albuquerque Flair Jose Carrilho Alberto Queiroz Farias | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，6： | 3 |
| 3 | Therapeutic and biological activities of Calotropis procera(Ait.) R.Br.显示文摘Medicinal plants have been used to treat various ailments of the poor population around the world;hence the interest among researchers to know the active ingredients of certain plants has being increased.The Calotropis procera(C.procera) is a plant original from Africa,commonly found in northeastern Brazil.It is well known for their pharmacological properties,since it produces large amounts of latex.The important role that medicinal plants play in folk medicine has led us to develop this article in order to review the major pharmacological activities of C. procera. | Marcia Calheiros Chaves Silva Antonio Batista da Silva Fabiano Moura Teixeira Paulo Cesar Pereira de Sousa Regina Maria Macedo Rondon Jose Eduardo Ribeiro Honorio Junior Luiz Rafael Leite Sampaio Samanda Lima Oliveira Angela Nadyla Martins Holonda Silvania Maria Mendes de Vasconcelos | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，4： | 2 |
| 4 | Taurine supplementation restores insulin secretion and reduces ER stress markers in protein-malnourished mice 显示文摘 | Batista TM da Silva PM Amaral AG | 2013 | Adv Exp Med Biol2013，776，1： | 1 |
| 5 | Comparative expression of RANK, RANKL, and OPG in keratocystic odontogenic tumors, ameloblastomas and dentigerous cysts 显示文摘 | da Silva TA Batista AC Mendon a EF | 2008 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2008，105，3： | 1 |
| 6 | Phytochemical study guided by the myorelaxant activity of the crude extract, fractions and constituent from stem bark of Hymenaea courbaril L.显示文摘 | Gabrieli Penha Bezerra Roberto Wagner da Silva Góis Teresinha Silva de Brito Francisco José Batista de Lima Mary Anne Medeiros Bandeira Nirla Rodrigues Romero Pedro Jorge Caldas Magalh?es Gilvandete Maria Pinheiro Santiago | 2013 | Journal of Ethnopharmacology2013，，： | 1 |
| 7 | The role of rhizobacteria in rice plants: Growth and mitigation of toxicity显示文摘Allelopathic compounds reduce the growth and productivity of upland rice plants, especially in consecutive plantations. The rhizobacteria Pseudomonas fluorescens BRM-32111 and Burkholderia pyrrocinia BRM-32113 have been recorded as growth promoters in rice. This study was developed to understand the effect of the application of rhizobacteria on upland rice plants in consecutive plantations. Experiments were conducted in a completely randomized design with four replications of four treatments: rice seed inoculated with P. fluorescens BRM-32111, rice seed inoculated with B. pyrrocinia BRM-32113(both sown on soil with rice residue), non-inoculated plants sown on soil with rice residue(control with residue(WR)), and non-inoculated plants on soil with no residue(NR). Roots and seedling growth were adversely affected by allelopathic compounds in control WR plants. Plants inoculated with rhizobacteria P. fluorescens BRM-32111 or B. pyrrocinia BRM-32113 induced an increase of 88% in biomass, 3% in the leaf area, 40% in length, 67% in root biomass, 21% in chlorophyll a, 53% in chlorophyll(a+b), 50% in rate of carbon assimilation(A), 227% in A/rubisco carboxylation efficiency(C_i) and 63% in water use efficiency(WUE) compared to control WR plants. These results indicate that rhizobacteria P. fluorescens BRM-32111 and B. pyrrocinia BRM-32113 increase the tolerance of rice plants to stress from allelochemicals. There are possible practical agricultural applications of these results for mitigating the effects of environmental allelochemistry on upland rice. | Marcela C F Rêgo Aline F Cardoso Thayná da C Ferreira Marta C C de Filippi Telma F V Batista Rafael G Viana Gisele B da Silva | 2018 | Journal of Integrative Agriculture2018，17，12： | 1 |
| 8 | Evaluation of the reproducibility in the inter-pretation of magnetic resonance images of the tem-poromandibular joint显示文摘 | Butzke KW Batista Chaves KD Dias da Silveira HE | 2010 | Dentomaxillofac Radiol2010，39，3： | 1 |
| 9 | Action of celecoxib on hepatic metabolic changes induced by the Walker-256 tumour in rats显示文摘 | Acco A Alves da Silva M H Batista M R | 2007 | Basic Clin Pharmacol Toxicol2007，101，5： | 1 |
| 10 | Acute bilinear leukemia: a rare disease with poor outcome 显示文摘 | Weir EG Ali Ansari-Lari M Batista DA | 2007 | Leukemia2007，21，11： | 1 |
| 11 | Improving the Ranking Quality of Medical Image Retrieval Using a Genetic Feature Selection Method 显示文摘 | da SILVA S R F RIBEIRO M X BATISTA NETO J E S | 2011 | Decision Support Systems2011，51，4： | 1 |
| 12 | Acute bilineal leukemia: a rare disease with poor outcome显示文摘 | Weir EG All Ansari-Lari M Batista DA | 2007 | Leukemia2007，21，11： | 1 |
| 13 | Low birth weight in Silo Luis, northeastern Brazil, trends and associated factors 显示文摘 | Helma Jane Ferreira Veloso Ant6nio Augusto Moura da Silva Helolsa Bettiol Marcelo Zubarin Goldani Fernando Lamy Filho Vanda Maria Ferreira Sim6es Rosgmgela Fernandes Lucena Batista Marco Ant6nio Barbieri | 2014 | BMC Pre Child2014，14，1： | 1 |
| 14 | Probiotic cheese:health benefits,technological and stability aspects显示文摘 | Gomes da Cruz A Alonso Buriti FC Batista de Souza CH | 2009 | Trends in Food Science & Technology2009，20，8： | 1 |
| 15 | Boosting Govern- ment Reputation Through CRM 显示文摘 | Rui da Silva Luciano Batista | 2007 | International Journal of Public Sector Management2007，，7： | 1 |
| 16 | Expression of Metalloproteinase 2 in the Cell Response to Porous Demineralized Bovine Bone Matrix显示文摘 | Thais Accorsi-Mendon?a Willian Fernando Zambuzzi Katiúcia Batista da Silva Paiva José Roberto Pereira Lauris Tania Mary Cestari Rumio Taga José Mauro Granjeiro | 2005 | Journal of Molecular Histology2005，，4： | 1 |
| 17 | Taurine supplementation restores insulin secretion and reduces ER stress markers in proteinmalnourished mice显示文摘 | Batista TM Da Silva PM Amaral AG | 2013 | Adv Exp Med Biol2013，776，： | 1 |
| 18 | Meloidogyne ingognita: Molecular cloning and characterization of a cDNA encoding a cathepsin D-like aspartic proteinase 显示文摘 | da Rocha Fragoso R Lourenco IT Nogueira Batista JA et d | 2009 | Exp Parasitol2009，121，2： | 1 |
| 19 | The Antinociceptive Effect of (-)-Linalool in Models of Chronic Inflammatory and Neuropathic Hypersensitivity in Mice显示文摘 | Patricia Aparecida Batista Maria Fernanda de Paula Werner Erica Carvalho Oliveira Leonel Burgos Patricia Pereira Lucimar Filot da Silva Brum Gina M. Story Adair R.S. Santos | 2010 | Journal of Pain2010，，： | 1 |
| 20 | Molecular identification of nontuberculous mycobacteria isolates in a Brazilian mycobacteria reference laboratory显示文摘 | Ana Roberta Fusco da Costa Maria Luiza Lopes Ismari Perini Furlaneto Maísa Silva de Sousa Karla Valéria Batista Lima | 2010 | Diagnostic Microbiology & Infectious Disease2010，，4： | 1 |
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