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| 1 | Metabolomic studies of human gastric cancer:Review显示文摘Metabolomics is a field of study in systems biology that involves the identification and quantification of metabolites present in a biological system. Analyzing metabolic differences between unperturbed and perturbed networks, such as cancerous and noncancerous samples, can provide insight into underlying disease pathology, disease prognosis and diagnosis. Despite the large number of review articles concerning metabolomics and its application in cancer research, biomarker and drug discovery, these reviews do not focus on a specific type of cancer. Metabolomics may provide biomarkers useful for identification of early stage gastric cancer, potentially addressing an important clinical need. Here, we present a short review on metabolomics as a tool for biomarker discovery in human gastric cancer, with a primary focus on its use as a predictor of anticancer drug chemosensitivity, diagnosis, prognosis, and metastasis. | Naresh Doni Jayavelu Nadav S Bar | 2014 | World Journal of Gastroenterology2014，20，25： | 19 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Thermal Frontiers in the Design and Packaging Microelectronic Equipment显示文摘 | Cohen A Bar Kraus A D Davidson S F | 1983 | Mechanical Engineering1983，105，6： | 1 |
| 4 | Efficacy,tolerability,and effects on quality of life of losartan,alone or with hydrochlorothiazide,in patients with essential hypertension显示文摘 | Bar E Elkins M | 1996 | Clin Ther1996，18，： | 1 |
| 5 | Telescopically retained removable parlial denlures on CAD/CAM generated all-ceramic primarylelescopes显示文摘 | Bar G Reich S | 2008 | lnt J Com- put Denl2008，11，2： | 1 |
| 6 | Insulin-like growth factor (IGF)-binding protein-4 proteolytic degradation in bovine,equine,and porcine preovulatory follicles:regulation by IGFs and heparin-binding domain-containing peptides显示文摘 | Zapf J Bar RS | 2000 | Biology of Reproduction2000，63，： | 1 |
| 7 | Genetics of resistance to insects in crop plants显示文摘 | Khus G S Bar D S | 1991 | Adv Agro1991，45，： | 1 |
| 8 | A single Ataxia Telangiectasia gene with a product similar to PI - 3 kinase 显示文摘 | Savitsky A Bar shira A Gilad S | 1995 | Science1995，268，： | 1 |
| 9 | Regulation of pH in the intestine of the laying fowl显示文摘 | HURWITZ S BAR A | 1968 | Poultry Science1968，47，： | 1 |
| 10 | ABL-specific tyrosine kinase inhibitor imatinib as salvage therapy in a child with Philadelphia chromosomepositive acute mixed lineage leukemia ( AMLL ) 显示文摘 | Selle B Bar C Hecker S | 2002 | Leukemia2002，16，7： | 1 |
| 11 | Protective effect of Bax ablation against cell loss in the retinal ganglion layer induced by optic nerve crush in transgenic mice显示文摘 | Goldenberg-Cohen N Dratviman-Storobinsky O Dadon Bar E1 S | 2011 | J Neuroophthalmol2011，31，： | 1 |
| 12 | Influence of olanzap- ine on QT variability and complexity measures of heart rate in pa- tients with schizophrenia 显示文摘 | BAR K J KOSCHKE M BERGER S | 2008 | J Clin Psychopharmacol2008，28，6： | 1 |
| 13 | Supression of natural killer cell activity and promotion of tumor metastasis by ketamine, thiopental, and halothane, but not by propofol : mediating mechanisms and prophylactic measure 显示文摘 | MALAMED R BAR YOSEF S SHAKHAR G | 2003 | Anesth Analg2003，97，5： | 1 |
| 14 | Ability of thermo-philic lactic add bacteria to produce aroma compounds from amino ac-ids 显示文摘 | HELINCK S LE BARS D MOREAU D | 2004 | Applied and Environmental Microbiology2004，70，7： | 1 |
| 15 | Sodium and chloride requirements of the 7-9-week-old broiler显示文摘 | HURWITZ S COHEN I BAR A | 1974 | Poultry Science1974，53，1： | 1 |
| 16 | Oral administ ration of inf luenza vaccine in combination with the adjuvants LT K63 and LTR72 induces po tent immune responses compar able to or stronger than traditional intramuscular immunization 显示文摘 | Bar ackman J D Ott G Pine S | 2001 | ClinVaccine Immunol2001，8，3： | 1 |
| 17 | Nasal and bronchial response to exercise in children with seasonal allergic rhinitis out of the pollen season显示文摘 | Koray Harmanc? Bar?s Urhan Hülya An?l Abdulkad?r Kocak | 2015 | Int Forum Allergy Rhinol2015，，： | 1 |
| 18 | The Interacting Multiple Model Algorithm for Systems with Markovian Switching Coefficients显示文摘 | Blom H A P Bar S Y | 1988 | IEEE Transactions on Automatic Control1988，33，8： | 1 |
| 19 | Bone morphogenetic protein-2 Induces the expression of cementum at tachment- protein in human periodontal ligament clones 显示文摘 | Pitaru S Pritzki A Bar Kana I | 2002 | Connect Tissue Res2002，43，23： | 1 |
| 20 | Acute generalized exanthematous pustulosis induced by high-dose prednisalone in a young woman with optic neuritis owing to disseminated encephalomyelitis显示文摘 | Bar L John S Wonschi K | 2008 | British Journal of Dermatology2008，159，1： | 1 |
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