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| 1 | Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fibrosis显示文摘AIM:To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI) imaging as a noninvasive method for the assessment of liver fibrosis in chronic hepatitis C (CHC) patients.METHODS:We performed a prospective blind com-parison of ARFI elastography,APRI index and FibroMax in a consecutive series of patients who underwent liver biopsy for CHC in University Hospital Bucharest. His-topathological staging of liver fibrosis according to the METAVIR scoring system served as the reference. A to-tal of 74 patients underwent ARFI elastography,APRI index,FibroMax and successful liver biopsy. RESULTS:The noninvasive tests had a good correlation with the liver biopsy results. The most powerful test in predicting fibrosis was ARFI elastography. The diagnostic accuracy of ARFI elastography,expressedas area under receiver operating characteristic curve (AUROC) had a validity of 90.2% (95% CI AUROC = 0.831-0.972,P < 0.001) for the diagnosis of significant f ibrosis (F ≥ 2). ARFI sonoelastography predicted even better F3 or F4 fibrosis (AUROC = 0.993,95% CI = 0.979-1).CONCLUSION:ARFI elastography had very good accuracy for the assessment of liver fibrosis and was superior to other noninvasive methods (APRI Index,FibroMax) for staging liver fibrosis. | Carmen Fierbinteanu-Braticevici Dan Andronescu Radu Usvat Dragos Cretoiu Cristian Baicus Gabriela Marinoschi | 2009 | World Journal of Gastroenterology2009，15，44： | 114 |
| 2 | History of polio vaccination显示文摘Poliomyelitis is an acute paralytic disease caused by three poliovirus(PV)serotypes.Less than 1%of PV infections result in acute flaccid paralysis.The disease was controlled using the formalin-inactivated Salk polio vaccine(IPV)and the Sabin oral polio vaccine(OPV).Global poliomyelitis eradication was proposed in 1988by the World Health Organization to its member states.The strategic plan established the activities required for polio eradication,certification for regions,OPV cessation phase and post-OPV phase.OPV is the vaccine of choice for the poliomyelitis eradication program because it induces both a systemic and mucosal immune response.The major risks of OPV vaccination are the appearance of Vaccine-Associated Paralytic Poliomyelitis cases(VAPP)and the emergence of Vaccine Derived Polioviruses strains.The supplementary immunization with monovalent strains of OPV type 1 or type 3 or with a new bivalent oral polio vaccine b OPV(containing type1 and type 3 PV)has been introduced in those regions where the virus has been difficult to control.Most countries have switched the schedule of vaccination by using IPV instead of OPV because it poses no risk of vaccine-related disease.Until 2008,poliomyelitis was controlled in Romania,an Eastern European country,predominantly using OPV.The alternative vaccinationschedule(IPV/OPV)was implemented starting in September 2008,while beginning in 2009,the vaccination was IPV only.The risk of VAPP will disappear worldwide with the cessation of use of OPV.The immunization for polio must be maintained for at least 5 to 10 years using IPV. | Anda Baicus | 2012 | World Journal of Virology2012，1，4： | 2 |
| 3 | Diastotic heart failure-abnormalities in active ralaxation and passive stiffness of the left ventricle显示文摘 | Zile MR Baicu CF Gaasch WH | 2004 | NEJM2004，350，19： | 1 |
| 4 | Diastolic heart failure - abnormalities in active relaxation and passive stiffness of the left ventricle显示文摘 | Zile MR Baicu CF Gaasch WH | 2004 | N Engl J Med2004，350，19： | 1 |
| 5 | Current state of hypothermic machine perfusion preservation of organs: The clinical perspective显示文摘 | Taylor M J Baicu S C | 2010 | Cryobiology2010，60，3： | 1 |
| 6 | Fever of unknown origin- predictors of outcome a prospective muhicenter study on 164 patients 显示文摘 | Baicus C Bolosiu HD Tanasescu C | 2003 | Eur J Intern Med2003，14，4： | 1 |
| 7 | Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle显示文摘 | Zile MR Baicu CF Gaasch WH | 2004 | NEJM2004，350，19： | 1 |
| 8 | Diastolic heart failue abnormalities in active relaxation and passive stiffness of the left ventricle 显示文摘 | Zile MR BaiCU CF Gaasch WH | 2004 | NEJM2004，350，5： | 1 |
| 9 | Current state of hypothermic machine perfusion preservation of organs:the clinical perspective显示文摘 | Taylor MJ Baicu SC | 2010 | Cryobiology2010，，3： | 1 |
| 10 | Clinical prediction rule for dif- ferentiating tuberculous from viral meningitis显示文摘 | Hristea A Olaru ID Baicus C et at | 2012 | Int J Tuberc Lung Dis2012，16，6： | 1 |
| 11 | Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure显示文摘 | Zile MR Desantis SM Baicu CF | 2011 | Circ Heart Fail2011，4，3： | 1 |
| 12 | Diastolic heart failure abnomalities in active relaxation and passive stiffness of the left ventricle 显示文摘 | Zile MR Baicu CF Gaasch WH | 2004 | N Engl J Med2004，350，19： | 1 |
| 13 | Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition 显示文摘 | Poobalarahi F Baicu CF Bradshaw AD | 2006 | Am J Physiol Heart Circ Physiol2006，291，6： | 1 |
| 14 | Pressure-overload induced alterations in fibrillar collagen content and myocardial diastolic function:role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing显示文摘 | Bradshaw AD Baicu CF Rentz TJ | | 0，，02： | 1 |
| 15 | Fever of unknown origin-predictors of outcome A prospective multicenter study on 164patients显示文摘 | Baicus C Bolosiu HD Tanasescu C | 2003 | Eur J Int Med2003，14，4： | 1 |
| 16 | Pressure-overload induced alterations in fibrillar collagen content and myocardial diastolic function 显示文摘 | Bradshaw AD Baicu CF Rentz TJ | 2009 | Circulation2009，119，2： | 1 |
| 17 | Cardiac-restricted overexpression or deletion of tissue in- hibitor of matrix metalloproteinase-4 : differential effects on left ventricular structure and function following pressure o- verload-induced hypertrophy 显示文摘 | YARBROUGH W M BAICU C MUKHERJEE R | 2014 | Am J Physiol Heart Circ Physio12014，307，5： | 1 |
| 18 | Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure显示文摘 | Zile MR Desantis SM Baicu CF | | 0，，03： | 1 |
| 19 | Effects of Gene Deletion of the Tissue Inhibitor of the Matrix Metalloproteinase-type 1 (TIMP-1) on Left Ventricular Geometry and Function in Mice显示文摘 | Lisa Roten Shintaro Nemoto Janet Simsic Mytsi L Coker Vijay Rao Simona Baicu Gilberto Defreyte Paul J Soloway Michael R Zile Francis G Spinale | 2000 | Journal of Molecular and Cellular Cardiology2000，，1： | 1 |
| 20 | Review of vitreous islet cryopreservation:some practical issues and their resolution显示文摘 | Taylor MJ Baicu S | 2009 | Organogenesis2009，5，： | 1 |
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