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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | DMSO extraction of sulfones from selectively oxidized fuels 显示文摘 | Bonde S E Dolbear G E | 1999 | Preprints1999，44，2： | 2 |
| 3 | Gold on titania catalysts for the oxidation of carbon monoxide : Control of pH during preparation with various gold contents显示文摘 | MOREAU F BOND G C TAYLOR A O | 2005 | Journal of Catalysis2005，231，1： | 1 |
| 4 | Catalysis by gold显示文摘 | BOND G C THOMPSON D T | 1999 | Catal Rev-Sci Eng1999，41，34： | 1 |
| 5 | The fate of human malignant melanoma cells transplanted into zebrafish embryos:assessment of migration and cell division in the absence of tumor formation显示文摘 | LEE L M J SEFTOR E A BONDE G | 2005 | Developmental Dynamics2005，233，4： | 1 |
| 6 | A pervasive millennial-scale cycle in north Atlantic Holocene and glacial climates 显示文摘 | Bond G Showers W Cheseby M | 1997 | Science1997，278，： | 1 |
| 7 | Myocardial matrix degradation and metalloproteinase activation in the failing heart:a potential therapeutic target显示文摘 | Spinale F G Coker M L Bond B R | 2000 | Cardiovasc Res2000，46，2： | 1 |
| 8 | An inventory of gaseous and primary aerosol emissions in Asia in the year 2000 显示文摘 | Streets D G Bond T C Carmichael G R | 2003 | Jour nal of Geophysical Research2003，108，21： | 1 |
| 9 | Correlations between climate records from North Atlantic sediments and Greenland ice显示文摘 | Bond G Broecker W Johnsen S | 1993 | Nature1993，365，： | 1 |
| 10 | Gold on titania cata- lysts for the oxidation of carbon monoxide: control of pH during preparation with various gold contents 显示文摘 | Moreau F Bond G C Taylor A O | 2005 | Journal of Catalysis2005，231，1： | 1 |
| 11 | Persistent solar influence on North Atlantic climate during the Holocene 显示文摘 | Bond G Kromer b Beer J | 2001 | Science2001，294，： | 1 |
| 12 | Correlations between climate records from North Atlantic sediments and Greenland ice显示文摘 | Bond G Broecker W Johnsen S | 1993 | Nature1993，365，： | 1 |
| 13 | Catalysis by gold显示文摘 | BOND G C THOMPSON D T | 1999 | Catal Rev Sci Eng1999，41，34： | 1 |
| 14 | An Investigation ofEnvironmental and Sustainability Discourses Associated withthe Substantive Purposes of Environmental Assessment 显示文摘 | RozemaJ G Bond A J Cashmore M | 2012 | Environmental Impact Assessment Review2012，33，： | 1 |
| 15 | Palladlum-catalysed reduction of molybdenum trioxide by hydrogen显示文摘 | Bond G C Tripathi J B P | 1974 | J Less-Common Met1974，36，12： | 1 |
| 16 | 2003, An inventory of gaseous and primary aerosol emissions in Asia in the year 2000 显示文摘 | Streets D G Bond T C Carmichael G R | 2003 | Journal of Geophysical Research-Atmospheres2003，108，88： | 1 |
| 17 | Forecasting cosmic parameter errors from microwave background anisotropy experiments显示文摘 | Bond J R Efstathiou G Tegmark M | 1997 | Astron Soc1997，291，： | 1 |
| 18 | Correlations between climate records from North Atlantic sediments and Greenland ice显示文摘 | Bond G Broecker W Johnsen S McManus J Labeyrie L Jouzel J Bonani G | | 0，，： | 1 |
| 19 | Five hundred intestinal transplantations at a single center:Major advance with new challenges显示文摘 | Abu-Elmagd K Costa G Bond GJ | 2009 | Ann Surg2009，250，4： | 1 |
| 20 | Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis principal results of the european lacidipine study on atherosclerosis (ELSA),a randomized,double-blid,long-term trial显示文摘 | ZANCHETTI A BOND M G HENNIG M | 2009 | Circulation2009，106，： | 1 |
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