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| 1 | Antihyperglycemic effect of Hypericum perforatum ethyl acetate extract on streptozotocin-induced diabetic rats显示文摘Objective:To evaluate the antihyperglycemic activity of ethyl acetate extract of Hypericum perforatum(H.perforatum)in streptozotocin(STZ)-induced diabetic rats.Methods:Acute toxicity and oral glucose tolerance lest were performed in normal rats.Male albino rats were rendered diabetic by ST/(40 mg/kg,intraperitoneally).H.perforatum ethyl acetate extract was orally administered to diabetic rats at SO,100 and 200 mg/kg doses for 15 days to determine the antihyperglycemic activity.Biochemical parameters were determined at the end of the treatment.Results:H.perforatum ethyl acetate extract showed dose dependant fall in fasting blood glucose(FBG).After 30 min of extract administration,FBG was reduced significantly when compared with normal rats.H.perforatum ethyl acetate extract produced significant reduction in plasma glucose level,serum total cholesterol,triglycerides,glucose-6-phosphatase levels.Tissue glycogen content,HDL-cholesterol,glucose-6-phosphate dehydrogenase were significantly increased compared with diabetic control.No death or lethal effect was observed in the toxic study.Conclusions:The results demonstrate that H.perforatum ethyl acetate extract possesses potent antihyperglycemic activity in STZ induced diabetic rats. | Arokiyaraj S Balamurugan R Augustian P | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，5： | 9 |
| 2 | Optical and Structural Properties of Nanocrystalline Copper Oxide Thin Films Prepared by Activated ReactiveEvaporation显示文摘 | Balamurugan B Mehta B R | 2001 | Thin Solid Films2001，396，： | 1 |
| 3 | Preservation of human islet cell functional mass by anti-oxidativeaction of a novel SOD mimic compound显示文摘 | BOTTINO R BALAMURUGAN A N BERTERA S | 2002 | Journal of Diabetes2002，51，8： | 1 |
| 4 | Development of an indirect ELISA for the detection of antibodies against peste-des-petits-ruminants virus in small ruminants显示文摘 | Balamurugan V Singh R P Saravanan P | 2007 | Vet Res Commun2007，31，3： | 1 |
| 5 | Optical and Structural Properties of Nanocrystalline Copper Oxide Thin Films Prepared by Activated Reactive Evaporation显示文摘 | Balamurugan B Mehta B R | 2001 | Thin Solid Films2001，396，12： | 1 |
| 6 | Protective immune response of the capsid precursor polypeptide(P1)of foot and mouth disease virus type‘O’produced in Pichia pastoris显示文摘 | BALAMURUGAN V RENJI R SAHA S N | 2003 | Virus Research2003，92，2： | 1 |
| 7 | Increased protein glycation in non-diabetic pediatric nephrotic syndrome: Possible role of lipid peroxidation显示文摘 | Bobby Z Selvaraj N | 2003 | Clin Chim Acta2003，337，12： | 1 |
| 8 | Protective immune response of the capsid precursor polypeptide (P1)of Foot and mouth disease virus type O' produced in Pichia pastoris显示文摘 | Balamurugan V Renji R Saha S N | 2003 | Virus Res2003，92，： | 1 |
| 9 | Optical and structural proper- ties of nanocrystalline copper oxide thin films prepared by activated reactive evaporation显示文摘 | Balamurugan B Mehta B R | 2001 | Thin Solid Films2001，396，12： | 1 |
| 10 | Pulsed electromagnetic field (PEMF)treatment for fracture healing显示文摘 | Boopalan P R J V C Chittaranjan Samuel B Balamurugan Ramada- ss | 2009 | Current Orthopaedic Practice2009，20，4： | 1 |
| 11 | The DNA methylation patterns in bisulfite modification and pyrosequencing 显示文摘 | Madi T Balamurugan K determination of tissuespecific forensic biofluids using Bombardi R | 2012 | Electrophoresis2012，33，： | 1 |
| 12 | Harmonic Optimization by Single Phase Improved Power Quality AC-DC Power Factor Corrected Converters显示文摘 | Balamurugan R Gurusamy G | | 0，，05： | 1 |
| 13 | A real-time hardware fault detector using an artificial neural network for distance protection显示文摘 | Venkatesan R Balamurugan B | 2001 | IEEE Transactions on Power Delivery2001，16，1： | 1 |
| 14 | Probiotic administration alters the gut flora and attenuates colitis in mice administered dextran sodium sulfate显示文摘 | NANDA KUMAR NS BALAMURUGAN R JAYAKANTHAN K | | 0，，12： | 1 |
| 15 | Multi-objective trajectory planner for industrial robots with payload constraints 显示文摘 | Saravanan R Ramabalab S Balamurugan C | 2008 | Robotica2008，26，： | 1 |
| 16 | Modifying the Nanocrystalline Characteristics-Structure,Size,and Surface States of CopperOxide Thin Films by High-Energy Heavy-Ion Irradiation显示文摘 | Balamurugan B Mehta B R Avasthi D K | 2001 | Journal of Applied Physics2001，92，6： | 1 |
| 17 | Prservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound显示文摘 | Bottino R Balamurugan AN Bertera S | 2002 | Diabetes2002，51，8： | 1 |
| 18 | Presser-vation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound显示文摘 | BALAMURUGAN A N BERTERA S | 2002 | Diabetes2002，51，8： | 1 |
| 19 | Development of a N gene-based PCR ELISA for detection of peste-des-petits ruminants virus in clinical samples显示文摘 | SARAVANAN P SINGH R P BALAMURUGAN V | 2004 | Acta Virol2004，48，4： | 1 |
| 20 | Response of human islets to isolation stress and the effect of antioxidant treatment显示文摘 | BOTTINO R BALAMURUGAN A N TSE H | 2004 | Diabetes2004，53，10： | 1 |
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