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| 1 | Improved guided bone regeneration by combined application of unmodified, fresh autologous adipose derived regenerative cells and plasma rich in growth factors:A first-in-human case report and literature review显示文摘BACKGROUND Novel strategies are needed for improving guided bone regeneration(GBR) in oral surgery prior to implant placement, particularly in maxillary sinus augmentation(GBR-MSA) and in lateral alveolar ridge augmentation(LRA). This study tested the hypothesis that the combination of freshly isolated, unmodified autologous adipose-derived regenerative cells(UA-ADRCs), fraction 2 of plasma rich in growth factors(PRGF-2) and an osteoinductive scaffold(OIS)(UAADRC/PRGF-2/OIS) is superior to the combination of PRGF-2 and the same OIS alone(PRGF-2/OIS) in GBR-MSA/LRA.CASE SUMMARY A 79-year-old patient was treated with a bilateral external sinus lift procedure as well as a bilateral lateral alveolar ridge augmentation. GBR-MSA/LRA was performed with UA-ADRC/PRGF-2/OIS on the right side, and with PRGF-2/OIS on the left side. Biopsies were collected at 6 wk and 34 wk after GBRMSA/LRA. At the latter time point implants were placed. Radiographs(32 mo follow-up time) demonstrated excellent bone healing. No radiological or histological signs of inflammation were observed. Detailed histologic,histomorphometric, and immunohistochemical analysis of the biopsies evidenced that UA-ADRC/PRGF-2/OIS resulted in better and faster bone regeneration than PRGF-2/OIS.CONCLUSION GBR-MSA with UA-ADRCs, PRGF-2, and an OIS shows effectiveness without adverse effects. | ?nder Solakoglu Werner G?tz Maren C Kiessling Christopher Alt Christoph Schmitz Eckhard U Alt | 2019 | World Journal of Stem Cells2019，11，2： | 3 |
| 2 | Formation of disulfide bonds in acid-induced gels of preheated whey protein isolate显示文摘 | ALTING A C HAMER R J DE C G | 2000 | J Agric Food Chem2000，48，10： | 1 |
| 3 | The Management of Appendiceal Mass in Children: Is Interval Appendectomy Necessary?显示文摘 | ?rfan Karaca Zekai Alt?ntoprak Ayta? Kark?ner Günyüz Temir Erol Mir | 2001 | Surgery Today2001，，8： | 1 |
| 4 | Control sensor linearization using artificial neural networks 显示文摘 | DEMPSEY G L ALT N J OLSON B A | 1997 | Analog Integrated Circuits and Signal Processing1997，13，3： | 1 |
| 5 | Dinuclear ansa-zirconocene complexes containing a sandwich and a half-sandwich moiety as catalysts for the polymerization of ethlylene显示文摘 | Alt H G Ernst R Bohmer I K | 2002 | J Organomet Chem2002，658，12： | 1 |
| 6 | Number of thiol groups rather than the size of the aggregates determines the hardness of cold set whey protein gels显示文摘 | ALTING A C HAMER R J DEKRUIF C G | 2003 | Food Hydrocolloids2003，17，4： | 1 |
| 7 | Design for assembly and dis- assembly显示文摘 | BOOTHROYD G ALTING L | 1992 | CIRP Annals Manufacturing Technology1992，41，2： | 1 |
| 8 | The influence of the ligand structure on the properties of (alpha - diimine)nieket catalysts in the polymerization and oligomerization of ethylene 显示文摘 | HELLDORFER M BACKHAUS J ALT H G | 2003 | Inorg Chim Ae- ta2003，351，： | 1 |
| 9 | Dinuclear Ansa Zirconocene Complexes Containing a Sandwich and a Half-Sandwich Moiety as Catalysts for the Polymerization of Ethylene显示文摘 | Alt H G Ernst R Bohmer I K | 2002 | J Organomet Chem2002，658，12： | 1 |
| 10 | Palonosetron triggers 5 - HT(3) receptor internalization and causes prolonged inhibition of receptor function 显示文摘 | ROJAS C THOMAS A G ALT J | 2010 | Eur J Pharmacol2010，626，3： | 1 |
| 11 | Asymmetric Dinuclear Ansa Zirconocene Complexes with Methyl and Phenyl Substituted Bridging Silicon Atoms as Dual Site Catalysts for the Polymerization of Ethylene显示文摘 | Alt H G Ernst R | 2003 | Inorg Chim Acta2003，350，4： | 1 |
| 12 | Matching planar maps 显示文摘 | ALT H EFRAT A ROTE G | 2003 | Journal of Algorithms2003，49，： | 1 |
| 13 | Lipid peroxidation, eryth rocyte superoxide dismutase activity and trace metals in young male footballers显示文摘 | Meti G Atukeren P Alt urfan AA | 2003 | Yonsei Med J2003，44，6： | 1 |
| 14 | Inter- acting with 21 st-century computers 显示文摘 | A Schmidt B Pfleging F Alt A Sahami G Fitzpatrick | 2012 | IEEE Pervasive Com- puting2012，11，1： | 1 |
| 15 | Formation of disulfide bonds in acid-induced gels of preheated whey protein isolate 显示文摘 | Alting A C Hamer R J de Kruif C G | 2000 | Journal of Agricultural and Food Chemistry2000，48，10： | 1 |
| 16 | Life cycle management and assessment: Approaches and visions towards sustainable manufacturing 显示文摘 | WESTKAEMPER E ALTING L ARNDT G | 2000 | CIRP Annals-Manufacturing Technology2000，49，2： | 1 |
| 17 | Mono, di and tetranuclear ansa zirconocene complexes as catalysts for the homogeneous and heterogeneous polymerization of ethylene 显示文摘 | ALT H G ERNST R BOHMER I | 2003 | Journal of Molecular Catalysis2003，191，： | 1 |
| 18 | Formation of disul?debondsin acid-induced gels of preheated whey protein isolate显示文摘 | Alting A C Hamer R J Kruif C G | | 0，，48： | 1 |
| 19 | The synthesis, characterization and polymerization behavior of ansa cyclopentadienyl fluorenyl complexes; the X-ray structures of the complexes ZrCl2(R = Me or Ph) 显示文摘 | Konstantinos P Helmut G Alt | 1996 | J Org Chem1996，509，： | 1 |
| 20 | Contributors to a multivariate statistical process control chart signal显示文摘 | RUNGER G C ALT F B MONTGOMERY I) C | 1996 | Communications in Statistics : Theory and Methods1996，25，10： | 1 |
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