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| 1 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 2 | Migrated endoclip and stone formation after cholecystectomy:A new danger of acute pancreatitis显示文摘Endoclip migration into the common bile duct following laparoscopic cholecystectomy (LC) is an extremely rare complication. Migrated endoclip into the common bile duct can cause obstruction,serve as a nidus for stone formation,and cause cholangitis. We report a case of obstructive jaundice and acute biliary pancreatitis due to choledocholithiasis caused by a migrated endoclip 6 mo after LC. The patient underwent early endoscopic retrog-rade cholangiopancreatography (ERCP) with endoscopic sphincterotomy and stone extraction. | Kemal Dolay Halil Alis Aliye Soylu Gulum Altaca Ersan Aygun | 2007 | World Journal of Gastroenterology2007，13，47： | 6 |
| 3 | Thermal and Magnetic Peculiarities of Metal-Containing Carbon Nano-Phase Formed in the Reaction of Fine-Dispersed Aluminium with Dichlorethane in Paraffin Medium显示文摘 | Hikmet C. Ibrahimov Joerg F. Friedrich Etibar H. Ismailov Eldar B. Zeynalov Aygun Z. Aliyeva Nadir M.I. Seidov Musa I. Rustamov | 2012 | 材料科学与工程(中英文A版)2012，2，2： | 3 |
| 4 | Association of Apolipoprotein E Polymorphisms in Patients with Non-Alcoholic Steatohepatitis显示文摘 | Ali Sazci Gurler Akpinar Cem Aygun Emel Ergul Omer Senturk Sadettin Hulagu | 2008 | Digestive Diseases and Sciences2008，，12： | 3 |
| 5 | Serum levels of hepatoprotective peptide adiponectin in non-alcoholic fatty liver disease显示文摘 | Cem Aygun Omer Senturk Saadettin Hulagu Suleyman Uraz Altay Celebi Tolga Konduk Birsen Mutlu Zeynep Canturk | 2006 | European Journal of Gastroenterology & Hepatology2006，，2： | 2 |
| 6 | Serum iron level and hepatic iron overload in nonalcoholic steatohepatitis and chronic viral hepatitis 显示文摘 | Uraz S Aygun C Sonsuz A | 2005 | Dig Dis Sci2005，50，5： | 1 |
| 7 | Effect of timing, IBA and Putrescine on rooting and shooting in Pyrus elaeagri folia pall softwood cuttings 显示文摘 | Dumano GH Aygun AA Gunes NT | 1999 | Hort Sic1999，69，11： | 1 |
| 8 | Sublingual sildenafil in the treatment of erectile dysfunction: faster onset of action with less dose显示文摘 | Deveci S Peskircioglu L Aygun C | 2004 | Int J Urol2004，11，11： | 1 |
| 9 | Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions显示文摘 | Aygun B Padmanabhan S Paley C | 2002 | Transfusion2002，42，1： | 1 |
| 10 | Use of phototherapy for neonatal hyperbilirubinemia affects cytokine production and lymphocyte subsets 显示文摘 | Kurt A Aygun AD Kurt AN | 2009 | Neonatology2009，95，3： | 1 |
| 11 | Serum procalcitonin level and other biological markers to distinguish between bacterial and aseptic meningitis in children显示文摘 | Dubos F Korczowski B Aygun DA | 2008 | Arch Pediatr Adolesc Med2008，162，12： | 1 |
| 12 | A two-level plane wave time-domain algorithm for fast analysis of EMC/EMI problems显示文摘 | Kemal Aygun | 2002 | IEEE Transactions on Electromagnetic Compatibility2002，44，1： | 1 |
| 13 | Environmental con tamination during a carbapenem- resistant Acinetobacter bau manii outbreak in an intensive care unit显示文摘 | Aygun G Demirkiran O Utku T | 2002 | J Hosp Infect2002，25，4： | 1 |
| 14 | Temporal bone fractures 显示文摘 | SARAIYA PV AYGUN N | 2009 | Emerg Radiol2009，16，： | 1 |
| 15 | Introduction to Fuzzy Soft Groups 显示文摘 | Aygunohlu A Aygun H | 2009 | Computer and Mathematics Application2009，58，6： | 1 |
| 16 | Introduction to fuzzy soft groups显示文摘 | Aygunoglu A Aygun H | 2009 | Computers & Mathematics with Applications2009，58，6： | 1 |
| 17 | Effects of processing conditions on the dielectric properties of Ca Cu3Ti4O12显示文摘 | Aygun S Tan X L Maria J P | 2005 | Journal of Electroceramics2005，15，3： | 1 |
| 18 | Magnesium Sulfate Pretreatment Reduces Myoclonus After Etomidate 显示文摘 | Aygun Guler Tulin Satilmis Seda BA | 2005 | Anerthetic pharmacology2005，101，： | 1 |
| 19 | A RECQS-RNA polymerase II association identified by targeted proteomie analysis of human ehromatin显示文摘 | Aygun O Svejstrup J Liu Y | 2008 | Proe Natl Aead Sei USA2008，105，25： | 1 |
| 20 | Pelvic retroperitoneal angioleiomyoma mimicking a uterine mass 显示文摘 | Esra Ozkavukcu Serhat AygUn Ayse Erden | 2009 | Diagn Interv Radiol2009，15，4： | 1 |
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