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| 1 | 急性缺血性卒中的机械取栓治疗:ESO、ESMINT、ESNR和EAN共同支持的2014/2015 ESO-卡罗林斯卡卒中更新会议共识声明显示文摘这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织(European Stroke Organisation, ESO)-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排,在2015年利用新的临床试验数据对该声明进行了更新。2015年2月,在瑞士伯尔尼召开的ESO冬季培训会期间组织了面对面会议对共识声明进行修订,然后通过电子邮件交换意见,最终版本得到各学会的认可。推荐意见与原始版本一致,证据等级更新到2015年2月20日为止,在2015年5月15日获得确认。ESO-卡罗林斯卡卒中更新会议的目的在于总结卒中治疗研究的最新进展并探讨如何将这些最新研究结果应用于临床实践。共识会议选择了一些议题进行讨论,与会者草拟一份共识声明并进行讨论。该声明接受了ESO指南委员会的指导。这份共识声明包括对急性卒中后机械取栓治疗的推荐意见,得到欧洲卒中组织ESO、欧洲神经微创治疗学会(European Society of Minimally Invasive Neurological Therapy, ESMINT)、欧洲神经放射学学会(European Society of Neuroradiology, ESNR)和欧洲神经病学学会(European Academy of Neurology, EAN)的支持。 | Nils Wahlgren Tiago Moreira Patrik Michel Thorsten Steiner Olav Jansen Christophe Cognard Heinrich P Mattle Wim van Zwam Staffan Holmin Turgut Tatlisumak Jesper Petersson Valeria Caso Werner Hacke Mikael Mazighi Marcel Arnold Urs Fischer Istvan Szikora Laurent Pierot Jens Fiehler Jan Gralla Franz Fazekas Kennedy R Lees 高洁 徐格林 | 2016 | 国际脑血管病杂志2016，24，1： | 5 |
| 2 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015，5，4： | 3 |
| 3 | Review on observational studies of western tropical Pacific Ocean circulation and climate显示文摘The Western Tropical Pacific(WTP) Ocean holds the largest area of warm water(>28℃) in the world ocean referred to as the Western Pacific Warm Pool(WPWP),which modulates the regional and global climate through strong atmospheric convection and its variability.The WTP is unique in terms of its complex 3-D ocean circulation system and intensive multiscale variability,making it crucial in the water and energy cycle of the global ocean.Great advances have been made in understanding the complexity of the WTP ocean circulation and associated climate impact by the international scientific community since the 1960 s through field experiments.In this study,we review the evolving insight to the 3-D structure and multi-scale variability of the ocean circulation in the WTP and their climatic impacts based on in-situ ocean observations in the past decades,with emphasis on the achievements since 2000.The challenges and open que stions remaining are reviewed as well as future plan for international study of the WTP ocean circulation and climate. | HU Dunxin WANG Fan SPRINTALL Janet WU Lixin RISER Stephen CRAVATTE Sophie GORDON Arnold ZHANG Linlin CHEN Dake ZHOU Hui ANDO Kentaro WANG Jianing LEE Jae-Hak HU Shijian WANG Jing ZHANG Dongxiao FENG Junqiao LIU Lingling VILLANOY Cesar KALUWIN Chalapan QU Tangdong MA Yixin | 2020 | Journal of Oceanology and Limnology2020，38，4： | 3 |
| 4 | Persistent Subclinical Hypothyroidism and Cardiovascular Risk in the Elderly: The Cardiovascular Health Study显示文摘 | Kristen A. Hyland Alice M. Arnold Jennifer S. Lee Anne R. Cappola | 2013 | The Journal of Clinical Endocrinology & Metabolism2013，，2： | 2 |
| 5 | Adverse Effect of Ventricular Pacing on Heart Failure and Atrial Fibrillation Among Patients With Normal Baseline QRS Duration in a Clinical Trial of Pacemaker Therapy for Sinus Node Dysfunction显示文摘 | Michael O. Sweeney Anne S. Hellkamp Kenneth A. Ellenbogen Arnold J. Greenspon Roger A. Freedman Kerry L. Lee Gervasio A. Lamas | 2003 | Circulation2003，，23： | 2 |
| 6 | Adverse Effect of Ventricular Pacing on Heart Failure and Atrial Fibrillation Among Patients With Normal Baseline QRS Duration in a Clinical Trial of Pacemaker Therapy for Sinus Node Dysfunction显示文摘 | Michael O. Sweeney Anne S. Hellkamp Kenneth A. Ellenbogen Arnold J. Greenspon Roger A. Freedman Kerry L. Lee Gervasio A. Lamas | 2003 | Circulation2003，，23： | 1 |
| 7 | The possible role of cyto-chrome coxidase in stress-induced apoptosis and degenerative disea-ses显示文摘 | Kadenbach B Arnold S Lee I | 2004 | Biochim Biophys Acta2004，1655，13： | 1 |
| 8 | The possible role of cytochromec oxidase in stress-induced apoptosis and degenerative diseases显示文摘 | Kadenbach B Arnold S Lee I | 2004 | Biochim Biophys Acta2004，1655，123： | 1 |
| 9 | Incidence of nonarteritic anterior ischemic optic neuropathy: increased risk among diabetic patients 显示文摘 | Lee MS Grossman D Arnold AC | 2011 | Ophthalmology2011，118，5： | 1 |
| 10 | Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase 1 1 This article is dedicated to the memory of the late Professor Lars Ernster.显示文摘 | Bernhard Kadenbach Maik Hüttemann Susanne Arnold Icksoo Lee Elisabeth Bender | 2000 | Free Radical Biology and Medicine2000，，3： | 1 |
| 11 | Persistent subclinical hypothyroidism and cardiovascular risk in the elderly : the cardiovascular health study显示文摘 | Hyland KA Arnold AM Lee JS | 2013 | J Clin Endocrinol Metab2013，98，： | 1 |
| 12 | The possiblerole of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases 显示文摘 | Kadenbach B Arnold S Lee I | 2004 | Biochimica et Biophysica Acta2004，1655，13： | 1 |
| 13 | Adverse Effect of Ventricular Pacing on Heart Failure and Atrial Fibrillation Among Patients With Normal Baseline QRS Duration in a Clinical Trial of Pacemaker Therapy for Sinus Node Dysfunction显示文摘 | Michael O. Sweeney Anne S. Hellkamp Kenneth A. Ellenbogen Arnold J. Greenspon Roger A. Freedman Kerry L. Lee Gervasio A. Lamas | 2003 | Circulation2003，，23： | 1 |
| 14 | Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults:the cardiovascular health study显示文摘 | Garin M C Arnold A M Lee J S | 2014 | J Clin Endocrinol Metab2014，99，8： | 1 |
| 15 | Olfactory epithe- lium amyloid-heta and paired helical filament-tau pathology in Alzheimer disease显示文摘 | Arnold SE Lee EB Moberg PJ etal | 2010 | Ann Neurol2010，67，4： | 1 |
| 16 | The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases显示文摘 | Kadenbach B Arnold S Lee I | 2004 | Biochim Biophys Acta2004，1665，13： | 1 |
| 17 | Antibiotic Stewardship in the Intensive Care Unit显示文摘 | Heather Arnold Scott Micek Lee Skrupky Marin Kollef | 2011 | Semin Respir Crit Care Med2011，，02： | 1 |
| 18 | The development of multiplex simple sequence repeat (SSR) markers to complement distinctness, uniformity and stability testing of rape (Brassica napus L.) varieties显示文摘 | L. Tommasini J. Batley G. Arnold R. Cooke P. Donini D. Lee J. Law C. Lowe C. Moule M. Trick K. Edwards | 2003 | Theoretical and Applied Genetics2003，，6： | 1 |
| 19 | Effects of dissolved oxygen and iron aging on the reduction of trichloronitromethane, trichloracetonitrile, and trichloropropanone 显示文摘 | Lee J Y Hozalski R M Arnold W A | 2007 | Chemosphere2007，66，11： | 1 |
| 20 | Tolerance Rather Than Immunity Protects From Helicobacter pylori– Induced Gastric Preneoplasia显示文摘 | Isabelle C. Arnold Josephine Y. Lee Manuel R. Amieva Axel Roers Richard A. Flavell Tim Sparwasser Anne Müller | 2011 | Gastroenterology2011，，1： | 1 |
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