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| 1 | 国际糖尿病足工作组:糖尿病足感染诊断与治疗指南——《国际糖尿病足工作组:糖尿病足防治国际指南(2019)》的一部分显示文摘国际糖尿病足工作组(IWGDF)从1999年开始发布糖尿病足病防治指南。本指南是有关糖尿病足感染的诊断和治疗的指南,是在2015年糖尿病足感染指南基础上更新的。糖尿病足感染指南编辑委员会基于患者-干预-比较-结局(PICO)原则,整合内部与外部专家顾问的建议,并对2016年以后有关糖尿病足感染和处治的文献进行系统评价后,提出了27条推荐要点。这些推荐要点涵盖了软组织与骨组织感染的诊断,包括感染的严重性分级。这是IWGDF15年以来第一次对这个分级表进行更新。此外,指南还评估了糖尿病足感染的微生物学,包括如何收集标本及如何识别致病菌。最后,指南讨论了治疗糖尿病足感染的方法,包括经验性抗生素的选择、软组织和骨组织感染的抗微生物治疗、何时和如何进行外科处理以及各种辅助治疗对糖尿病足感染的有效性。本版指南在原指南的基础上更新了4个表格和1个图。我们认为该指南可以为糖尿病足感染的临床诊断和治疗提供更好的帮助。 | Benjamin A.Lipsky Eric Senneville Zulfqarali G.Abbas Javier Aragón-Sánchez Mathew Diggle John M.Embil Shigeo Kono Lawrence A.Lavery Matthew Malone Suzanne A.van Asten Vilma Urbancic-Rovan Edgar J.G.Peters 无 徐俊(译) 许樟荣(审校) | 2019 | 感染.炎症.修复2019，20，4： | 18 |
| 2 | Interleukin-1 and TNF-α polymorphisms and Helicobacter pylori in a Brazilian Amazon population显示文摘AIM:To study the association between Interleukin-1(IL-1)and tumor necrosis factor(TNF)-αpolymorphisms,infection by Helicobacter pylori(H pylori)and the development of gastrointestinal diseases.METHODS:Genomic DNA was extracted from the peripheral blood of 177 patients with various gastrointestinal diseases and from 100 healthy volunteers.The polymorphisms in IL-1βand TNF-αgenes were analyzed using the polymerase chain reactionrestriction fragment length polymorphism method(PCRRFLP)and those from IL-1RN with PCR.The presence of infection due to H pylori and the presence of the CagA toxin were detected by serology.The histopathological parameters in the gastric biopsies of the patients were according to the Sydney classification.RESULTS:A comparison of the frequencies of the different polymorphisms studied among the patients and the control group demonstrated that the allele IL1RN*2 was more frequent among patients with gastric ulcers and adenocarcinoma.Carriers of the allele ILRN*2 and those with reactive serology for anti-CagA IgG had a greater risk of developing peptic ulcer and gastric adenocarcinoma,as well as a higher degree of inflammation and neutrophilic activity in the gastric mucosa.CONCLUSION:Our results indicate a positive association between IL-1RN gene polymorphism and infection by positive H pylori CagA strains and the development of gastric ulcers and adenocarcinoma. | Hivana Patricia Melo Barbosa Luisa Caricio Martins Sidney Emanuel Batista dos Santos Samia Demachki Mnica Baraúna Assumpo Charliana Damasceno Arago Tereza Cristina de Oliveira Corvelo | 2009 | World Journal of Gastroenterology2009，15，12： | 17 |
| 3 | A study of fire propagation in coal seam with numerical simulation of heat transfer and chemical reaction rate in mining field显示文摘Spontaneous combustion of coal is a problem that affects the mining operation and generates environ-mental,economic,social and geotechnical impacts.This phenomenon has been divided into two pro-cesses:ignition and propagation.Fire propagation develops in coal seams because of a set of factors such as direction and wind speed,fracturing and temperature.In this work,heat transfer and chemical kinetics are studied from conservation equations of energy and species,respectively,using the software COMSOL Multiphysics to simulate the propagation of fires in coal seams.Two possible scenarios were analyzed that usually occur in the walls of the coal seams,such as fire focus and fire complete screens.It was found that the propagation kinetics of the fire changes depending on the temperature,the fractur-ing of rock mass and the area of fire influence.For temperature values lower than 300℃,there is con-sumption around 250 cm^3/h,values around 700℃,the consumption is 1500 cm^3/h,and for fires of 1200℃ have values of 3000 cm^3/h.Depending on the speed of propagation can vary from 4 to 17cm/day,considering on the level and fracturing of the final wall of the open pit. | Moisés Oswaldo Bustamante Rúa Alan José Daza Aragón Pablo Bustamante Baena | 2019 | International Journal of Mining Science and Technology2019，29，6： | 8 |
| 4 | Pathophysiology of cystic fibrosis and drugs used in associated digestive tract diseases显示文摘Cystic fibrosis(CF)causes chronic infections in the respiratory tract and alters the digestive tract.This paper reviews the most important aspects of drug treatment and changes in the digestive tract of patients with CF.This is a review of the literature,emphasizing the discoveries made within the last 15 years by analyzing scientific papers published in journals indexed in the Scientific Electronic Library Online,Sciences Information,United States National Library of Medicine and Medical Literature Analysis and Retrieval System Online databases,both in English and Portuguese,using the key words:cystic fibrosis,medication,therapeutic,absorption,digestion.Randomized,observational,experimental,and epidemiological clinical studies were selected,among others,with statistical significance of 5%.This review evaluates the changes found in the digestive tract of CF patients including pancreatic insufficiency,constipation and liver diseases.Changes in nutritional status are also described.Clinical treatment,nutritional supplementation and drug management were classified in this review as essential to the quality of life of CF patients,and became available through public policies for monitoring and treating CF.The information gathered on CF and a multi professional approach to the disease is essential in the treatment of these patients. | Adriana Haack Giselle Gonalves Arago Maria Rita Carvalho Garbi Novaes | 2013 | World Journal of Gastroenterology2013，19，46： | 7 |
| 5 | Determinants of neonatal jaundice in Ethiopia:a systematic review and meta-analysis显示文摘Background Neonatal jaundice is a common condition characterized by a yellowish discoloration of the skin,conjunctiva,and sclera caused by elevated serum or plasma bilirubin levels during the newborn period.The condition is usually not dangerous,but it can progress to severe hyperbilirubinemia,which can lead to acute bilirubin encephalopathy and kernicterus,a bilirubin-induced neurological damage.Therefore,this study aimed to assess the pooled prevalence of neonatal jaundice and its determinants in Ethiopia.Methods Scopus,PubMed,Google Scholar,Embase,and CINAHL databases were searched for studies published between January 1,2010 and July 30,2021.A weighted DerSimonian Laird random-effects model was used to estimate the pooled prevalence of neonatal jaundice and its associated factors.The I2 was used to calculate the degree of heterogeneity.The funnel plot and Egger's regression test were used to assess publication bias.Results Totally 697 articles were generated from various databases,and the review included a total of eight articles.The pooled prevalence of neonatal jaundice was 30.96%[95%confidence interval(CI)16.61%–45.31%)]in Ethiopia.This review showed that prolonged labor[adjusted odd ratio(AOR)=3.39;95%CI 2.41–4.77),low birth weight(AOR=5.12;95%CI 3.11–8.72),birth asphyxia(AOR=3.75;95%CI 2.11–6.66),cephalohematoma(AOR=7.07;95%CI 2.72–18.38),ABO incompatibility(AOR=6.05;95%CI 2.95–12.42),Rhesus(RH)incompatibility(AOR=3.77;95%CI 2.04–6.96),male sex(AOR=4.53;95%CI 3.39–6.07),and neonatal sepsis(AOR=2.47;95%CI 1.49–4.08)were identified as a determining factor for neonatal jaundice in Ethiopia.Conclusions In low-and middle-income countries,neonatal jaundice is a significant healthcare burden,accounting for a significant portion of global childhood mortality and morbidity.However,some low-cost,effective,practical,and dependable solutions have been implemented.Prolonged labor,ABO incompatibility,RH incompatibility,birth asphyxia,neonatal sepsis,low birth weight,cephalohematoma,and male sex were identified as risk factors for neonatal jaundice in Ethiopia. | Habtamu Gebrehana Belay Getachew Arage Debebe Alemu Degu Ayele Bekalu Getnet Kassa Gedefaye Nibret Mihretie Mulugeta Dile Worke | 2022 | World Journal of Pediatrics2022，18，11： | 3 |
| 6 | Modification in the diet can induce beneficial effects against breast cancer显示文摘The population tends to consume foods that in addition to their nutritional values can offer some benefits to their health. There are many epidemiological evidences and research studies in animal models suggesting that diet plays an important role in breast cancer prevention or progression. This review summarized some of the relevant researches about nutrition and cancer during the last years, especially in breast cancer. The analysis of probiotics and fermented products containing lactic acid bacteria in cancer prevention and/or treatment was especially discussed. It was observed that a balance of fatty acids similar to those of traditional Mediterranean diet, the consumption of fruits and vegetables, dietary fiber intake, vitamin supplementation are, along with the intake of probiotic products, the most extensivelystudied by the negative association to breast cancer risk. The consumption of probiotics and fermented products containing lactic acid bacteria was associated to reduce breast cancer risk in some epidemiological studies. The use of animal models showed the modulation of the host's immune response as one of the important effects associated to the benefices observed with most probiotics. However; future assays in human are very important before the medical community can accept the addition of probiotic or fermented milks containing lactic acid bacteria as supplements for cancer patients. | Felix Aragón Gabriela Perdigón Alejandra de Moreno de Le Blanc | 2014 | World Journal of Clinical Oncology2014，5，3： | 2 |
| 7 | 副猪嗜血杆菌的流行病学和分型显示文摘澳大利亚和新西兰是泛太平洋地区最大的两个国家。两国的家禽产量数一数二。当前,产业整合是大趋势,肉蛋消费量也在增加。然而,肉蛋产品的价格处于压力下。动物福利越来越受重视。 | 赵瑜 Virginia Aragón | 2012 | 国外畜牧学(猪与禽)2012，，2： | 2 |
| 8 | C-reactive protein as an indicator of sepsis显示文摘 | P. Póvoa E. Almeida P. Moreira A. Fernandes R. Mealha A. Arag?o H. Sabino | 1998 | Intensive Care Medicine1998，，10： | 2 |
| 9 | Proactive Corporate Environmental Strategies: Myths and Misunderstandings显示文摘 | Juan Alberto Aragón-Correa Enrique A. Rubio-López | 2007 | Long Range Planning2007，，3： | 1 |
| 10 | The combination of micron and nanotopography by H2SO4/H2O2 treatment and its effects on osteoblastspecific gene expression of hMSCs显示文摘 | Mendon?a G Mendon?a DB Arag?o FJ | 2010 | J Biomed Mater Res A2010，94，1： | 1 |
| 11 | Comparison of metaraminol, phenylephrine and ephedrine in prophylaxis and treatment of hypotension in cesarean section under spinal anes- thesia显示文摘 | Aragao FF Arag o PW Martins CA | 2014 | Braz J Anesthesiol2014，64，5： | 1 |
| 12 | The effect of director interlocks on firms'adoption of proactive environmental strategies显示文摘 | Natalia Ortiz-de-Mandojana Aragón-Correa J A Delgado-Ceballos J | 2012 | Corporate Governance:An International Review2012，20，2： | 1 |
| 13 | Advancing dental implant surface technology- From micron- to nano-topography显示文摘 | MENDON~A G MENDON(~A D B S ARAG~ O F J L COOPER L F | 2008 | Biomaterials2008，29，28： | 1 |
| 14 | Proactive corporate environmental strategies:Myths and misunderstandings显示文摘 | Aragón-Correa J A Bubio-López E A | 2007 | Ling Range Planning2007，40，3： | 1 |
| 15 | Advancing dental implant surface technology--from micron-to nanotopography显示文摘 | Mendon?a G Mendon?a DB Arag?o FJ | | 0，，28： | 1 |
| 16 | A Contingent Resource-BasedView of Proactive Corporate Environmental Strategy显示文摘 | Aragón-Correa J A Sharma S | 2003 | Academyof Management Review2003，28，1： | 1 |
| 17 | Advancing dental implant surface technology from micron- to nanoto- pography 显示文摘 | Mendon~a G Mendonca DB Arag~o FJ | 2008 | Biomaterials2008，29，28： | 1 |
| 18 | Anti-microbial activity in vitro of plumbagin isolated from Plumbago species显示文摘 | de Paiva SR Figueiredo MR Arag?o TV Kaplan MA | | 0，，： | 1 |
| 19 | Structure,function and regulation of Glycine neurotransporters显示文摘 | Carmen Aragón Beatrie López-Corcuera | 2003 | European Journal of Pharmacology2003，479，13： | 1 |
| 20 | Proactive corporate environmental strategies:Myths and misunderstandings显示文摘 | Aragón-Correa J A Rubio-L6pez E A | 2007 | Long Range Planning2007，40，： | 1 |
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